社区获得性肺炎15种常见菌对22种抗菌药体外活性的研究  

A study of drug-sensitivities with 22 common antibiotics for 15 common bacteria in vitro of community acquired pneumonia

作　　者：廖晚珍[1] 彭卫华[1] 胡雪飞[1] 孙爱娣[1] 余阳[1] 温桂兰[2] 陈国华[2] 

机构地区：[1]南昌大学第一附属医院检验科,江西南昌330006 [2]南昌大学第一附属医院呼吸科,江西南昌330006

出　　处：《实验与检验医学》2009年第2期114-117,共4页Experimental and Laboratory Medicine

基　　金：江西省卫生厅基金资助(合同编号:041052)

摘　　要：目的掌握我省社区获得性肺炎(CAP)细菌谱和药敏谱,为我省提供治疗CAP的准确资料。方法细菌的分离与鉴定采用常规法和仪器法,最小抑菌浓度的检测采用琼脂稀释法。结果121例CAP检出病原体52例(42.90%),居前5位分别是肺炎链球菌、流感嗜血杆菌、肺炎克雷伯菌、铜绿假单胞菌、葡萄球菌和卡他莫拉菌(并列)。药敏中阳性菌和大多数阴性菌分别测14种抗菌素,嗜血杆菌和莫拉菌测9种抗菌素,基本上确定了常用药的药敏谱。结论CAP病原谱和药敏谱由于地区不同、人群不同、季节不同、诊治水平等不同,其组成和结果都有所不同,这个参数并不能判断每一种抗生素的最终疗效。Objective To find out the bacteria spectrum and drug-sensitivity spectrum of community acquired pneumonia（CAP） and offer accurate information for the treatment of CAP. Methods Using routine way isolated indentified bacteria, and agra dilution method measured minimal inhibitory concentration. Results 52 strains of bacteria were isolated from 121 CAP cases, the first fifth position of all pathogens were Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphyloeuccus and Moraxella catarrhalis. 14 kinds of antibiotics were used for detecting the drug-sensitivities of G-positive cocci and the most of G-negtive bacilli and with 9 kinds of antibiotics for Haemophilus and Moraxella. Conclusions The composition of pathogens and drug-sensitivity of CAP were different in area, crowd, season, the levels of diagnosis and treatment.

关 键 词：社区获得性肺炎 常见菌 常用抗菌药 体外活性 治疗 

分 类 号：R446.5[医药卫生—诊断学] Q939.92[医药卫生—临床医学]