用Pd-Fe/SiO_2常压催化加氢合成3-氟-4-氨基苯酚的研究  

Preparation of 3-Fluoro-4-Aminophenol by Catalytic Hydrogenation at Atmosphere Pressure Using as Pd-Fe/SiO_2 Catalyst

作　　者：周壮[1] 张晓伟[2] 

机构地区：[1]江苏安邦电化有限公司,江苏淮安223002 [2]淮阴工学院图书馆,江苏淮安223003

出　　处：《淮阴师范学院学报（自然科学版）》2009年第1期60-63,共4页Journal of Huaiyin Teachers College;Natural Science Edition

摘　　要：以自制的Pd-Fe/SiO2为催化剂,对3-氟-4-硝基苯酚常压催化加氢得到3-氟-4-氨基苯酚,用熔点、元素分析I、R和1H NMR对其结构进行了表征,并确认为目标产物.确定优化工艺条件为:0.1 mol硝基物,催化剂2.6 g/mol硝基物,无水乙醇作溶剂,用量为60 mL,反应温度为40℃,0.1 MPa下加氢反应3 h,收率为98.1%,产物的纯度达98.4%.Pd-Fe/SiO2 catalyst was prepared and used to catalysis the hydrogenation of 3-fluoro-4-nitrophenol at atmosphere pressure, which yields 3-fluoro-4-aminophenol. The product was characterized by means of IR, H NMR, melting point test, and elemental analysis, and proved to target product. The optimmn conditions was ex- plored to be as follows： 0.1 mol 3-fluoro-4-nitrophenol, 0.26g Pd-Fe/SiO2catalyst, 60 ml anhydrous alcohol as solvent. Under atmosphere pressure, the hydrogenation reaction lasts 3 hours at 40℃. The rate of production is 98.1%, and the purity of product reaches 98.4%.

关 键 词：Pd-Fe/SiO2催化剂 3-氟-4-氨基苯酚 催化加氢 常压 

分 类 号：O643.3[理学—物理化学]