艾滋病合并马尔尼菲青霉菌病20例临床分析  

A clinical analysis of 20 cases AIDS-associated Pencilliosis marneffei

作　　者：黄爱琼[1] 叶寒辉[1] 黄拯球 王争武 李圣聪[1] 

机构地区：[1]福州市传染病医院,350002 [2]福州市皮肤病医院

出　　处：《福建医药杂志》2009年第2期7-8,F0003,共3页Fujian Medical Journal

摘　　要：目的分析艾滋病(AIDS)合并马尔尼菲青霉菌病(PSM)临床表现,以提高对PSM的认识。方法回顾分析2007年2月～2008年8月收治的20例AIDS合并PSM患者临床表现,血培养或病理检查确诊马尔尼菲青霉菌(PM)。结果AIDS合并PSM的临床表现以发热、消瘦、咳嗽、咳痰、肝脾肿大、皮疹为主,特征性坏死性丘疹具有一定诊断意义,多数患者外周血CD4+T淋巴细胞计数小于50个/μl。结论了解PSM有助于临床诊断及治疗,我院AIDS合并PM感染率为24.7%。Objective To analyze the clinical manifestations of AIDS-associated PSM in order to improve recognition of PSM. Methods Twenty cases of AIDS-associated PSM admitted between February 2007 and August 2008 were retrospectively analyzed. PSM was diagnosed by culture separation or pathological examination. Results The clinical manifestations of AIDS- associated PSM included fever, weight loss, cough, expectoration, hepatosplenomegaly, skin rashes. Specific necrotic papular eruptions were helpful for diagnosis. Most patients had CD4^ ＋ T lymphocyte counts in peripheral blood less than 50 cells/μl. Conclusion Recognition of PSM help clinical diagnosis and treatment. The infection rate of PM associated with AIDS was 24.7% in our hospital.

关 键 词：获得性免疫缺陷综合征 马尔尼菲青霉菌病 

分 类 号：R512.91[医药卫生—内科学]