一步法合成2-甲基-4-戊烯-2-醇  

Synthesis of 2-Methyl-4-Penten-2-Ol in One-Step Process

作　　者：陈苗[1] 徐崇福[1] 朱晓斌[1] 

机构地区：[1]江苏工业学院化学化工学院,江苏常州213164

出　　处：《江苏工业学院学报》2009年第1期8-10,共3页Journal of Jiangsu Polytechnic University

基　　金：江苏工业学院科技基金(ZMF05020019)

摘　　要：对传统的两步法格氏反应合成2-甲基-4-戊烯-2-醇的工艺进行研究,提出混合溶剂一步法合成工艺。研究合成过程中溶剂、反应时间、反应温度等因素对2-甲基-4-戊烯-2-醇产率的影响,获得控制反应过程的最佳参数。用IR、1HNMR对产物的分子结构进行了表征。研究结果表明,采用混合溶剂一步法合成工艺,当V(苯)∶V(四氢呋喃)=3∶1时,产物2-甲基-4-戊烯-2-醇的产率达到81.3%。Studies of the technical aspect of synthesizing 2--methyl--4--penten--2--ol in traditional two --step process were carried out and a synthetic route using mixed solvents in one step was proposed. The effects of solvent types, reaction time, and reaction temperature on the yield of 2--methyl--4--penten--2 --ol were investigated in detail and the optimal parameters in controlling the process were determined. The molecular structure of the products was characterized with IR and 1 H NMR technology. It was shown that when the volume ratio of benzene to tetrahydrofurane was 3 to 1, the yield of 2--methyl--4--penten--2-- ol reached as much as 81.3%.

关 键 词：一步法 格氏反应 2-甲基-4-戊烯-2-醇 

分 类 号：TQ031.2[化学工程]