定痉灵、可乐必妥、泼尼松联合治疗输尿管小结石的疗效分析  

Analysis of the curative effects on No-SPA and ofloxacin combined with prednisone in the treatment of small ureteral calculi

作　　者：孙超 许可慰 黄海[2] 郭正辉[2] 江春[2] 韩金利[2] 李星智[2] 

机构地区：[1]湖南省宁乡县人民医院泌尿外科,湖南410600 [2]中山大学附属第二医院泌尿外科,广州510120

出　　处：《岭南现代临床外科》2009年第2期140-142,共3页Lingnan Modern Clinics in Surgery

摘　　要：目的探讨定痉灵、可乐必妥、泼尼松联合治疗输尿管小结石的排石效果。方法346例直径<0.6 cm输尿管结石患者随机分为治疗组和对照组。治疗组176例,对照组170。治疗组除多饮水及增加运动外,给予定痉灵40 mg tid、可乐必妥500 mg qd、泼尼松5 mg qd口服;对照组只是多饮水及增加活动。结果治疗组176例中有158例患者排出结石,有效率为89.8%。对照组170例中有130例患者排出结石,有效率为76.5%,两者存在统计学差异(P<0.01)。治疗组结石排出时间为(9.2±4.3)d,对照组为(12.3±5.7)d,两者存在统计学差异(P<0.01)。结论对于直径<0.6 cm的输尿管结石,定痉灵、可乐必妥、泼尼松联合治疗安全有效,可提高排石率,缩短排石时间。Objective To investigate the effects on No-SPA and ofloxacin combined with prednisone in the treatment of small ureteral calculi. Methods 346 patients with small ureteral calculi less than 0.6cm in diameter were randomly divided into therapeutic group and control group, The therapeutic group was 176 cases and control group was 170 cases. In the therapeutic group ,the No-SPA 40 mg tid and ofloxacin 500 mg qd combined with Prednisone 5mg qd for 7 days excepting for drinked more water and increased gymnastic activity. The control group drinked more water and increased gymnastic activity as well. Results In therapeutic group and control group, the ejection rates of calculi were in 89.9% and 76.5% respectively. There were statistical difference between two groups （P〈0.01）. Conclusion No-SPA and ofloxacin combined with prednisone are safety and effective method in treatment of small ureteral calculi.

关 键 词：输尿管结石 定痉灵 可乐必妥 泼尼松 

分 类 号：R693[医药卫生—泌尿科学]