利窍益智汤治疗轻度认知障碍32例临床研究  

Clinical Study on the Effect of Liqiao Yizhi Decoction in Treating 32 Cases of Mild Cognitive Impairment

作　　者：季向东[1] 储兴[1] 周振和[1] 

机构地区：[1]无锡市精神卫生中心中西医结合科

出　　处：《中医杂志》2009年第4期308-310,共3页Journal of Traditional Chinese Medicine

摘　　要：目的观察利窍益智汤治疗轻度认知障碍(MCI)的疗效。方法将32例MCI患者采用自拟利窍益智汤治疗(治疗组),与30例MCI患者采用西药吡拉西坦治疗(对照组)进行比较,观察两组治疗后记忆功能和认知功能疗效,以及相关量表积分的比较。结果两组MCI患者的认知功能、记忆功能及行为能力的积分均可以明显改善(P<0.01),且在行为能力积分方面治疗组优于对照组(P<0.05)。对MCI患者的记忆及认知功能的作用两组差异无统计学意义(P>0.05)。结论利窍益智汤对痰浊蒙窍、脾肾两虚证MCI有确切的疗效。Objective To observe effect of Liqiao Yizhi Decoction （Decoction for inducing resuscitation to improve cognition） on mild cognitive impairment （MCI）. Methods Treatment group （32 cases） was treated with Liqiao Yizhi Decoction, and the control group was treated by Piracetam. Memory, congnition and related scores of both groups were observed. Results Both groups were improved in the scores of cognition, memory and behavioral ability of MCI patients （P〈0.01）. While in improving the behavioral ability, the treatment group was better than the control group（P〈0.05）. Difference between groups in total effect, memory and congnition was not significant. Conclusion Liqiao Yizhi Decoction was effective for MCI with the syndrome of obstruction of orifias by phlegm turbidity.

关 键 词：利窍益智汤 痰浊阻窍 脾肾两虚 轻度认知障碍 中医药疗法 

分 类 号：R277.7[医药卫生—中医学]