毛细管气相色谱法测定海藻酸钠中的甲醇  

Determination of methanol in sodium algin by capillary gas chromatogram

作　　者：郝文[1] 

机构地区：[1]山东省青岛市疾病预防控制中心,山东青岛266033

出　　处：《中国卫生检验杂志》2009年第4期786-787,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的：建立海藻酸钠中甲醇的毛细管气相色谱测定方法。方法：海藻酸钠样品用水稀释,在酸性条件下蒸馏,将馏出液进入气相色谱仪,经DB-FFAP毛细管柱分离,FID检测器检测,峰面积定量。结果：本法对海藻酸钠样品检出限为0.035 mg/g,甲醇在0-2.0 mg/ml浓度范围内呈线性关系,平均回收率为100%,相对标准偏差（RSD）为1.3%-2.3%。结论：该法准确可靠,灵敏度高,可有效地检测海藻酸钠中甲醇的残留量。Objective：To establish a method for determination of methanol in sodium algin by capillary gas chromatogram. Methods：Sodium algin samples were diluted by water, distilled in acidity condition, entered into the instrument, separated on DB - FFAP capillary column and detected by FID detector, quantified by peak areas. Results ： With this method, detection limit （ S/N = 3） of sodium algin was 0. 035 mg/g. The calibration curve showed good linearity in the range of 0 - 2. 0 mg/ml. The mean recovery was 100% ,and the relative standard derivation was between 1.3% and 2. 3%. Conclusion：This method is sensitive and accurate. It can effectively determine the methanol residue in sodium algin.

关 键 词：毛细管气相色谱 海藻酸钠 甲醇 

分 类 号：O657.71[理学—分析化学]