应用血管内超声评价颈动脉粥样硬化与冠心病的相关性研究  

Study the Relationship Between Carotid and Coronary Atherosclerosis with Intravascular Ultrasound

作　　者：虞华鹏[1] 姜婕[1] 贾如意[1] 赵成军[1] 赵震[1] 

机构地区：[1]济南市第四人民医院济南市心血管病研究所,济南市心血管病治疗中心,济南250031

出　　处：《中国医药导刊》2009年第3期352-354,356,共4页Chinese Journal of Medicinal Guide

摘　　要：目的:通过体表颈动脉超声对颈动脉内中膜厚度(IMT)及颈动脉粥样硬化斑块的检测,结合冠状动脉造影(CAG)和血管内超声(IVUS)技术,探讨颈动脉粥样硬化病变的发生与冠心病的关系及对冠心病的预测价值。方法:38例被检查者均为住院接受冠脉造影及血管内超声检查的患者,应用高频超声检测IMT及粥样硬化斑块,将颈动脉超声指标与冠状动脉造影及血管内超声检查结果进行分析比较。结果:冠心病组的颈动脉硬化斑块的检出率明显高于对照组,且与冠脉病变的严重程度有关。不稳定型心绞痛组的颈动脉粥样硬化等级积分和Crouse积分,斑块数均明显高于非冠心病对照组及稳定型心绞痛组(P<0.01)。根据CAG和IVUS计算的冠状动脉Gensini积分与颈动脉粥样硬化等级积分和Crouse积分,斑块数均有显著相关性(P<0.01)。结论:颈动脉粥样硬化严重程度与冠心病成正相关。颈动脉超声检测对冠心病有一定的预测价值。Objective：Detecting the carotid artery in the intima- medial thickness （IMT） and carotid atherosclerotic plaque with Carotid artery ultrasound through the body surface, Combining coronary angiography and intravascular ultrasound technology to discuss the relationship between carotid atherosclerosis and coronary heart disease incidence and the predictive value of coronary heart disease. Methods： Choice of 38 cases of patients who accepted coronary angiography and intravascular ultrasound examination, Application of high-frequency ultrasonic testing IMT and atherosclerotic plaque to analyze and compare the results of carotid ultrasound indicators and coronary angiography and intravascular ultrasound examination. Results： The detection rate of carotid atherosclerosis plaque in CHD group was significantly higher and related with the severity of coronary artery disease. The carotid atherosclerosis grade integral, Crouse integral, Plaque volume in unstable angina group were significantly higher than the non-coronary heart disease group and the stable angina group （P〈0.01） .The coronary gensini integral according to the calculation of CAG and IVUS has a significant correlation with The carotid atherosclerosis grade integral, Crousc integral, Plaque volume （P〈0.01） . Conclusion： The severity of Carotid atherosclerosis and coronary heart disease has a positive correlation. Carotid ultrasound detection has some predictive value to coronary heart disease.

关 键 词：冠状动脉疾病 动脉粥样硬化 内中膜厚度(IMT) 超声检查 

分 类 号：R541.4[医药卫生—心血管疾病] R445.1[医药卫生—内科学]