无创通气治疗不同病因致急性呼吸衰竭的临床研究  

Noninvasive Ventilation Treatment of Acute Respiratory Failure Causes Different Clinical Research

作　　者：李安稳[1] 古利明[1] 蔡远玲[1] 潘琼兰[1] 

机构地区：[1]云南省玉溪市人民医院呼吸科,玉溪653100

出　　处：《中国医药导刊》2009年第3期408-410,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:研究无创通气对慢性阻塞性肺疾病、重症肺炎、心源性肺水肿、重症哮喘不同病因所致急性呼吸衰竭的治疗效果,评估无创机械通气在急性呼吸衰竭治疗中的作用。方法:在常规治疗的基础上采用无创机械通气治疗急性呼吸衰竭患者60例,其中慢性阻塞性肺疾病组15例,重症肺炎组15例,心源性肺水肿组15例,重症哮喘组15例,观察4组的治疗效果。结果:4组患者治疗后PaO_2改善均有显著性差异(P<0.05),临床症状缓解,其中慢性阻塞性肺疾病组、心源性肺水肿组、重症哮喘组气管插管率及病死率均明显低于重症肺炎组。结论:无创机械通气对慢性阻塞性肺疾病、重症肺炎、心源性肺水肿、重症哮喘所致急性呼吸衰竭的早期,治疗效果肯定,但最终预后因呼吸衰竭病理不同,重症肺炎组患者气管插管率及死亡率均明显高于其他三组。Objective： Study the treatment effect of the Noninvasive Ventilation （NIV） used to treat acute respiratory failure which caused by chronic bronchitis, severe pneumonia, acute pulmonary edema, and severe asthma. Evaluate the function of the Noninvasive Ventilation （NIV） in the treatment of acute respiratory failure. Methods： Based on the common treatment, use the Noninvasive Ventilation （NIV） to treat 60 patients with acute respiratory failure, among them, 15 cases with chronic bronchitis, 15 cases with severe pneumonia, 15 cases with acute pulmonary edema, 15 cases with severe asthma. And then observe the treatment effects of the four groups.Result： After the treatment, the PaO2 of the patients of four groups is improved and has significant differences （P〈0.05） The clinical symptoms are relieved. The rate of endotracheal intubation and mortality rate are significantly lower in chronic bronchitis, acute pulmonary edema, and severe asthma than those in severe pneumonia.Conclusion： Noninvasive Ventilation （NIV） has positive effect to the early stage of the acute respiratory failure caused by chronic bronchitis, severe pneumonia, acute pulmonary edema, and severe asthma.

关 键 词：无创机械通气 急性呼吸衰竭 重症肿炎 重症哮喘 心源性肺水肿 慢性阻塞性肺疾病 

分 类 号：R563.8[医药卫生—呼吸系统]