肾上腺盐皮质激素醛固酮对胰岛素分泌的影响  

The Correlationship Analys of Aldosterone and Type Ⅱ Diabetes Insulin Resistance

作　　者：姜秋菊[1] 陈奕名[2] 

机构地区：[1]北华大学附属医院核医学科,吉林132011 [2]北华大学第二附属医院内分泌科,吉林132021

出　　处：《中国医药导刊》2009年第4期585-586,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:用放射免疫方法测定2型糖尿病患者在不同发病阶段的醛固酮水平。研究和探讨了醛固酮激素对2型糖尿病胰岛素分泌的影响。方法:收集2006年～2007年住院的2型糖尿病(DM)患者,均符合WHO 2型糖尿病诊断标准,共计86倒。年龄(52.14±27.11);对照组为正常健康人群30例,年龄(46±13岁)。结果:发病早期的2型糖尿病人醛固酮水平增高,相关性分析显示醛固酮与胰岛素分泌具有高度相关;在发病的晚期,胰岛索和醛固酮水平均下降,有显著的统计学意义。结论:醛固酮影响胰岛素的分泌,并可能参与了胰岛索的抵抗和2型糖尿病的发生和发展。Objective：To study and discuss the effects of aldosterone to type Ⅱ diabetes with radioirnmunity method. In this method we mesure aldosterone level of type Ⅱ diabetes patients in different morbidity stage. Methods： To collect the data of DM of in -paiients in 2006 - 2007 and the data （sum up to 71 cases） match the standard of WHO type Ⅱ diabetes. Age of （50. 25 ±26. 01 ） ; Contrasting group is normal human with 30 cases, age of （46 ± 13 ）. Results： Aldosterone level is high in earlier morbidity DM patients. The correlation analyse shows high correlationship between aldosterone and insulin; in late morbidity stage the level of aldosterone and insulin is low. It has significance in this study. Conclusions ：Aldosterone affect insulin, and it may take part in the insulin resistance and the happening and the development type Ⅱ diabetes.

关 键 词：醛固酮 2型糖尿病 胰岛素 

分 类 号：R587.1[医药卫生—内分泌]