氨酚羟考酮片致头痛眩晕  

Headache and vertigo induced by oxycodone-acetaminophen tablets

作　　者：李坚[1] 赵淑清[1] 

机构地区：[1]北京大学第三医院神经科,北京100191

出　　处：《药物不良反应杂志》2009年第2期145-145,共1页Adverse Drug Reactions Journal

摘　　要：1例48岁女性患者同右小腿外伤后口服氨酚羟考酮片1片(每片含盐酸羟考酮5mg、对乙酰氨基酚500mg),1h后出现头晕。次日早餐后又服该药1片,1h后出现双颞部隐痛、眩晕、恶心、行走不稳,经静脉滴注川芎嗪、疏血通等治疗,7h后好转。当晚患者第3次服用氨酚羟考酮,再次出现同样症状,给予异丙嗪25mg肌内注射,症状缓解。停用氨酚羟考酮片,头痛、眩晕等症状未再复发。A 48-year-old woman received 1 oxycodone-acetaminophen tablet （containing oxycodone hydrochloride 5 mg and acetaminophen 500 mg） for right lower leg trauma. One hour later, she experienced dizziness. The next day, the patient received 1 oxycodone-acetaminophen tablet again after breakfast. One hour later, she presented with vague pain in her temples, vertigo, nausea, and unstable walking. She was administered an Ⅳ infusion of ligustrazine and an Ⅳ infusion of Shuxuetong. Seven hours later, she improved. In the evening, the patient developed the same symptoms after the third administration of 1 oxycodone-acetaminophen tablet. Her symptoms relieved after administration of IM promethazine 25 mg. Oxycodone-acetaminophen tablets were discontinued, and her headache and vertigo did not recur.

关 键 词：氨酚羟考酮 头痛 眩晕 不良反应 

分 类 号：R595.3[医药卫生—内科学]