2,4-二氯氟苯的合成  

SYNTHESIS OF 2, 4-DICHLOROFLUOROBENZENE

作　　者：韦正友[1] 陈江[1] 陈忠远[2] 

机构地区：[1]蚌埠医学院化学教研室,233003 [2]四通生物医药有限公司研究所

出　　处：《精细石油化工》1998年第3期22-24,共3页Speciality Petrochemicals

摘　　要：论述了2，4－二氯氟苯合成的新方法。以对氯硝基苯为起站原料，经氟化反应、硝化反应及氯化反应制得2，4-二氯氟苯，总收率达59．0％。本合成路线工艺简单、操作安全、原料易得、成本低廉，适合于工业化生产。A newsynthetic method of 2,4 -dichlorofluorobenzene was reported. By the starting material 4 -chloronitrobenzene, 2, 4 - dichlorobenzene was synthesized via fluorination, nitration and chlorina-tion. The total yield was 59. 0%. The present process was simple and suitable for the industrial pro-duction, with safe operation, available materials and low cost.

关 键 词：二氯氟苯 对氯硝基苯 抗菌药 合成 

分 类 号：TQ465.91[化学工程—制药化工]