不同减肥措施对非酒精性脂肪性肝病转归的影响  

Influence of different weight-losing measures on the outcome of nonalcoholic fatty liver disease.

作　　者：汤庆娅[1] 

机构地区：[1]上海交通大学医学院附属新华医院临床营养科,上海200092

出　　处：《中国实用内科杂志》2009年第5期402-405,共4页Chinese Journal of Practical Internal Medicine

摘　　要：肥胖是目前非酒精性脂肪性肝病(NAFLD)的常见原因,在全球其发病率近年来随着肥胖的盛行而迅猛增长。NAFLD与代谢综合征(MS)和胰岛素抵抗的关系密切。体重上升,尤其是腹腔内脂肪的增加是NAFLD和MS发生和进展的高危风险。对于肥胖相关的NAFLD患者,减肥是惟一有效的治疗方法,合理控制饮食,增加有氧运动,建立良好的心理行为是防治NAFLD的关键;目前还缺乏有关设计良好的药物和手术对肥胖相关的NAFLD的对照研究结论。Obesity is a common cause of nonalcoholic fatty liver disease （NAFLD）. Recently, the morbidity of NAFLD has increased rapidly worldwide, associated with obesity prevalence. NAFLD, metabolic syndrome （ MS ） and insulin resistance are closely related.The increase in weight, especially in visceral fat tissue,was the highest risk factor to cause NAFLD and MS, and for their progress. To NAFLD patients, the only effective measure is weight reduction, including reasonable diet and aerobic exercise. Moreover, a sound mentality and behavior are the key factors of the treatment of NAFLD. On the other hand, the literature lacks well-designed, randomized control trials that assess the efficacy of anti-obesity drug and weight-loss surgery on the long-term outcomes of NAFLD.

关 键 词：非酒精性脂肪性肝病 减肥 

分 类 号：R5[医药卫生—内科学]