吸烟与贵州老年男性人群血脂水平的关系研究  

The relationship between smoking and blood lipids in elderly males in Guizhou

作　　者：焦桂萍[1] 任雁京[1] 丁毅[1] 王秀荣[1] 高秀蓉[1] 谭新杰[1] 袁志柳[1] 

机构地区：[1]贵州省人民医院干部医疗科,贵州贵阳550002

出　　处：《中国老年学杂志》2009年第8期998-1000,共3页Chinese Journal of Gerontology

基　　金：贵州省优秀科技教育人才省长专项基金项目〔2005(25)号〕

摘　　要：目的探讨吸烟对贵州老年男性人群血脂水平的影响,为临床干预和健康教育提供资料。方法选取2004年1月～2006年12月在我科常规体检的贵州老年男性人群2160人,对其进行问卷调查、体格检查和血脂检查,包括年龄、吸烟史、饮酒史、体重指数(BMI)、血压等情况。对吸烟与总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白B(ApoB)和脂蛋白a〔Lp(a)〕的关系进行分析。结果当前吸烟者的TG水平〔(2.97±1.28)mmol/L〕明显高于不吸烟者〔(1.30±0.46)mmol/L〕和已戒烟者〔(1.32±0.78)mmol/L〕(P<0.001),而HDL-C水平〔(0.95±0.30)mmol/L〕却明显低于不吸烟者〔(1.24±0.40)mmol/L〕和已戒烟者〔(1.26±0.26)mmol/L〕(P<0.001)。当前吸烟者和已戒烟者的TG、TC及HDL-C水平异常与不吸烟者相比更常见。在将吸烟与其他影响血脂的因素(如饮酒、BMI、年龄)进行比较后发现,吸烟对血脂紊乱的影响最大(β=0.219),当对这些影响因素进行校正分析后发现吸烟是血脂紊乱的一个独立危险因素(P=0.032)。结论吸烟对贵州老年男性人群血脂水平具有重要的影响,从而引发动脉粥样硬化(AS)、心血管疾病和脑血管疾病。Objective To investigate the relationship between smoking and blood lipids in elderly males in Guizhou and provide information for clinic intervention and health education. Methods 2 160 elderly males were selected from January 2004 to December 2006. The questionnaire, physical examination and serum lipid examination were examined, including age, smoking history, alcohol intake, body mass index（BMI） and blood pressure. The relationship between smoking and triglycerides（TG）, total cholesterol （TC）, high-density lipoprotein cholesterol（ HDL-C ）, low-density lipoprotein cholesterol（ LDL-C ）, apoprotein B （ ApoB）, lipoprotein （a） [ Lp （a） ] were analysed. Results Levels of TG [ （2.97±1. 28 ） mmol/L] in current smokers were significantly higher and levels of HDL-C [ （0. 95 ± 0. 30） mmol/L] lower than those of who had never smoked or had stopped smoking（P 〈0. 001 ）. Levels of TG, TC and HDL-C in current smokers and those who had stopped smoking were more frequently abnormal than those of who had never smoked. When comparing with other factors that influence serum lipids, such as alcohol intake, BMI and age, smoking had the greatest influence（ β =0. 219） and was an independent risk factor for dyslipidaemia（P = 0. 032）. Conclusions Smoking has an important influence on serum lipids in elderly males in Guizhou and leads to the occurrence of artherosclerosis, cardiovascular and cerebral vascular disease.

关 键 词：吸烟 血脂紊乱 老年 男性 贵州 

分 类 号：R589.2[医药卫生—内分泌]