原发性醛固酮增多症筛查中血浆醛固酮／肾素活性比值的影响因素  

Influential factors on the ratio of plasma aldosterone concentration to plasma renin activity in screening primary aldosteronism

作　　者：鄞国书[1] 张少玲[1] 严励[1] 程桦[1] 

机构地区：[1]中山大学附属第二医院内分泌科,广州510120

出　　处：《中华内分泌代谢杂志》2009年第2期238-241,共4页Chinese Journal of Endocrinology and Metabolism

基　　金：基金项目：“十五”国家科技攻关计划（2004BA720A29）;广州市科委科技攻关计划（200523-C7601）

摘　　要：血浆醛固酮水平／肾素活性比值（ARR）是筛查原发性醛固酮增多症的实用指标。由于影响肾素和醛固酮分泌的因素众多，ARR切点值变异范围较大，至今仍然是一个缺乏标准化的指标。本文综述这些因素，旨在临床上提高ARR的诊断效力。The ratio of plasma aldosterone concentration to plasma renin activity （ARR） is a practical parameter in screening for primary aidosteronism （PA）. However, variations of the cutoff value of ARR in different studies have been reported due to plenty of influential factors that may affect the secretions of renin and aldosterone. Lack of standardization of assays for ARR also makes direct comparisons among different studies difficult. The associated influential factors on ARR were introduced in this review.

关 键 词：原发性醛固酮增多症 醛固酮 肾素 肾素-血管紧张素Ⅱ-醛固酮系统 

分 类 号：R586.24[医药卫生—内分泌] R972.1[医药卫生—内科学]