肺动脉局部狭窄对血液流动的影响  

Effect for a local stenosis in the pulmonary artery on the blood flow

作　　者：李莹[1] 罗先武[1] 李映男[1] 张明奎 刘树红[1] 许洪元[1] 

机构地区：[1]清华大学水沙科学与水利水电工程国家重点实验室,北京100084 [2]清华大学第一附属医院,北京100016

出　　处：《清华大学学报（自然科学版）》2009年第5期707-710,714,共5页Journal of Tsinghua University(Science and Technology)

基　　金：国家自然科学基金资助项目(50676044);北京市自然科学基金资助项目(3072008)

摘　　要：采用临床检查的CT影像资料建立肺动脉物理模型,应用计算流体力学的方法,对5种不同程度肺动脉狭窄情况下的血液流动进行数值模拟。结果表明:随着肺动脉的狭窄程度加剧,狭窄部位的截面面积减小,其中心流速越来越大;近壁面低速流线越来越少,说明边界层变薄;窄后部位出现回流现象,且越来越剧烈;窄前压力逐渐升高,窄后压力逐渐降低,狭窄前后的压差单调增加;壁面剪切力较大的区域增大,狭窄处的剪切力单调增大。因此,肺动脉狭窄对血液流动状态及相关血液动力学参数产生了重要的影响。A physical model of the pulmonary artery was created using CT pictures from a clinical examination. The blood flows with five types of pulmonary artery stenoses were analyzed using a CFD method. The results indicate that increasing the size of the stenosis reduced the section area at the stenotic site and greatly increased central velocity. The boundary layer near the vessel wall became thinner with increasing hack flow downstream of the stenosis. The static pressure upstream of the stenosis increased while that downstream decreased, so there was an increasing pressure difference between the upstream and downstream end of the stenotic site. The area with large wall shear stresses increased, with the wall shear stress increasing as the stenosis size increased. Thus, a stenosis in the pulmonary artery has an important effect on the blood flow and pressure drop.

关 键 词：血液流动 局部狭窄 肺动脉 

分 类 号：R331[医药卫生—人体生理学]