豚鼠膀胱Cajal样间质细胞肌层分布及相关功能分析  

The distribution and functions of interstitial cells of Cajal in guinea pig bladder

作　　者：朱国栋[1] 纪世琪[1] 丁国富[2] 王勤章[2] 

机构地区：[1]石河子大学医学院 [2]石河子大学医学院第一附属医院泌尿外科,新疆石河子832008

出　　处：《农垦医学》2009年第1期1-3,共3页Journal of Nongken Medicine

基　　金：国家自然科学基金(30860281)

摘　　要：目的:研究豚鼠膀胱Cajal样间质细胞分布、超微结构特点并探讨其功能。方法:选择健康豚鼠10只,利用激光共聚焦显微镜和透射电镜观察膀胱Cajal样间质细胞在肌层的分布和结构特点。结果:豚鼠膀胱肌层Cajal样间质细胞形成网状和平行状两种不同的分布。超微结构核大、具有丰富的细胞器。结论:膀胱Cajal样间质细胞分布和超微结构与胃肠道的ICCs相似,具有起搏细胞特征。Objective： To study the distribution and ultrastructure of interstitial ceils of Cajal （ICCs） in guinea pig bladder and to discusses its functions. Methods： Distribution and structural characteristics of interstitial cells of Cajal of the ten healthy guinea pigs were observed through .a laser - scanning confocal microscopy and electric microscopy. Results： There were 2 types of interstitial cells of Cajal in the bladder muscle of guinea pig which formed network and parallel distribution respectively. Uhrastructual analysis revealed that it has big uhrastructure nucleus and rich cell organs. Conclusion： The interstitial cells of Cajal in bladder have unique distribution and uhrastructure character. The distribution and ultrastructure of interstitial cells of Cajal in bladder is similar to the ICCs in the gastrointestinal tract, with revealed the characteristics of the pacemaker cells.

关 键 词：CAJAL样间质细胞 豚鼠 膀胱 

分 类 号：R322.62[医药卫生—人体解剖和组织胚胎学]