舍曲林治疗中学生强迫症临床分析  

Effect of Sertraline Tablets in the Treatment of Obsession

作　　者：倪俊芝[1] 李秀亮 孙佳[1] 

机构地区：[1]天津市第一中心医院心理科,中国300011 [2]天津市河北区新开河医院

出　　处：《中国健康心理学杂志》2009年第4期448-449,共2页China Journal of Health Psychology

摘　　要：目的观察舍曲林治疗中学生强迫症的疗效及副作用,为临床工作提供客观依据。方法采用耶鲁-布朗强迫量表YBOCS和副反应量表TESS分别评定疗效和副作用。结果观察治疗4周、8周时YBOCS总均分较治疗前(42.17±11.26)明显减少(21.03±5.28、11.21±3.05),有明显统计学差异(P<0.05,P<0.01);观察治疗8周时临床治愈率86.46%,副反应发生率28.57%。结论舍曲林治疗中学生强迫症疗效显著,副反应少,值得临床推广。Objective To observe the curative effect and side effect of sertralin in treatment of obsessino to provide an objective basis for the clinical work. Methods Yale--Brown force quantity scale （YBOCS） and side reaction quantity scale （TESS） were adopted to assess curative effect and side effect respectively. Results The total YBOCS scores obviously decreased （21.03±5.28, 11.21 ± 3.05） compared with prior treatment （42.17± 11.26） in 4 and 8 weekends after treatment, and showed obvious statistical differences （P〈0. 05 or 0. 01）,The clinical cure rate was 86.46% and the incidence rate of side reaction was 28.57% in 8 weekend after treatment. Conclusion Sertraline can treat depression with obvious effect and little side reaction and is worthy of clinical promotion.

关 键 词：舍曲林 中学生 强迫症 副反应量表 

分 类 号：R581.1[医药卫生—内分泌] R749.99[医药卫生—内科学]