肺结核患者院内获得性肺炎46例分析  

Analysis of 46 case with pulmonary tuberculosis complicated by hospital acquired pneumonia

作　　者：王晓兰[1] 

机构地区：[1]吉林市第二中心医院,132001

出　　处：《中国实用医药》2009年第12期49-50,共2页China Practical Medicine

摘　　要：目的探讨肺结核患者院内获得性肺炎病原菌分布和耐药性,为临床治疗院内获得性肺炎提供用药指导。方法对46例肺结核患者院内获得性肺炎58株病原菌资料进行回顾性分析。结果58株病原菌中,革兰阴性杆菌35株,占60.3%,其中铜绿假单胞菌17株,革兰阳性球菌15株,占25.9%,以金黄色葡萄球菌为主,真菌8株,占13.8%。常用抗菌素耐药率由高到低分别为头孢呋辛82.7%,头孢哌酮79.3%、头孢曲松69%、氧氟沙星51.7%、哌拉西林48.3%等,最高为头孢呋辛,最低为亚胺培南17.2%。同时耐两种以上抗菌素者28株占48.3%。结论肺结核患者院内获得性肺炎的主要病原菌为革兰阴性杆菌,对头孢呋辛的耐药率最高,对亚胺培南的敏感性最高,有的病原菌同时耐多种抗菌素。Objective To determine the etiology and bacterial resistance of pulmonary tuberculosis patients with hospital acquired pneumonia ,to direct the clinical treatment. Methods A retrospective analysis of patients. Bacterial 58 strains isolated from patients were analyzed Results The $8 strains ,60, 3% was Gramnegative bacilli , 7.3% pseudom-nas aencginosa ,25.9 Gram-positive cocci ,, most was staphy was Aureus . 13.8% Fungli,The sensitive rate of was 82.7%, cefoperazone was 79, 3%, cefatriaxon was 69% , ofloxacin was 57. 7% , piperacilliu was 48.3%. imipenem was 17, 2%. the bacterial resistance to other two rids antibiotic wrew 28 strains , it was 48.3%. Conclusion The main isolated pathogen from pulmonary tubericulosis are gram-negative baclli , and the bacterial resistance lute of which to cefuroxime is highest , to imipenem also high some bacteria were resistance to many antibitic.

关 键 词：肺结核 获得性肺炎 细菌 耐药 

分 类 号：R521[医药卫生—内科学] R563.1[医药卫生—临床医学]