贵州省2007年麻疹实验室网络运转状况分析  

Analysis on Running Status of Guizhou Provincial Measles Laboratory Network in 2007

作　　者：吴升伟[1] 叶绪芳[1] 张丽[1] 徐飞[1] 戴丽芳[1] 杜雯[1] 朱青[1] 

机构地区：[1]贵州省疾病预防控制中心,贵阳550004

出　　处：《中国疫苗和免疫》2009年第2期112-114,共3页Chinese Journal of Vaccines and Immunization

基　　金：贵州省卫生厅科学技术基金资助项目([2007]119-17)

摘　　要：目的评价贵州省2007年麻疹实验室网络(Measles Laboratory Network,MLN)运转情况。方法对贵州省2007年MLN的检测结果和麻疹监测系统(Measles Surveillance System,MSS)的数据进行分析。结果①血清学监测:贵州省2007年MSS共报告疑似麻疹1645例,其中1454例采集了血标本,标本采集率88.4%。麻疹病例915例,其中临床诊断191例,实验室确诊724例(占79.1%)。28起麻疹爆发中27起经实验室证实,占96.4%。监测健康人群血清麻疹IgG标本726份,阳性率70.3%,几何平均滴度为1:492.6。②病毒学监测:2007年共收集35份咽拭子或尿液标本,分离到11株麻疹病毒,经鉴定为H1a基因亚型。③MLN质量控制:2007年省疾病预防控制中心(CDC)麻疹实验室通过了中国CDC病毒病预防控制所国家麻疹实验室组织的职能考核、再证实试验及现场认证;9个地区级CDC麻疹实验室通过了省CDC组织的职能考核和现场认证,全省复核血清标本215份,202份与省CDC结果一致,符合率为94.0%。结论贵州省2007年MLN运转良好,并建立了比较健全的质量控制体系,在麻疹监测中发挥重要作用。Objective To evaluate the running status of the Guizhou provincial measles laboratory network in 2007. Methods To analyze the testing result of measles laboratory network and data of measles Surveillance system（MSS）. Results 1. Serologic surveillance：1645 suspected measles cases were reported in MSS in 2007, and 1454 measles sera samples were collected, and the collection rate was 88.4%.The measles cases were 915, among 191 were diagnosed by clinic, and 724 were confirmed by laboratory（79.1%）. 27 of 28 outbreaks were laboratory diagnosed as measles. The measles IgG of 726 healthy population sera were tested, and the positive rate was 70.3%. and geometric mean titer was 1：492.6. 2.Viruology surveillance： from 35 throat swab or urine samples collected in 2007, 11 strains of wild measles virus were isolated, all of them were Hla genotype. 3. Laboratory network quality control： the provincial Center for Disease Control and Prevention （CDC） measles laboratory passed the proficiency test, the sera samples recheck and on-site review held by the China CDC National Measles Laboratory with good performance in 2007. Nine prefectures CDC measles laboratories passed the sera proficiency test and on-site review held by the provincial CDC. 215 sera samples were rechecked, among which, 202 result was as same as the provincial laboratory, the accordance rate was 94.0%. Conclusion Running status of the whole provincial measles laboratories network were good in 2007, and the good laboratory quality control system was also set up, and they play an important role in measles surveillance.

关 键 词：麻疹实验室网络 血清学监测 病毒学监测 质量控制 

分 类 号：R373.3[医药卫生—病原生物学]