电化学DNA生物传感器研究的应用进展  

Development of Electrochemical DNA Biosensors

作　　者：黄强[1] 刘红英[1] 方宾[1] 

机构地区：[1]安徽师范大学化学与材料科学学院化学生物传感安徽省重点实验室,芜湖241000

出　　处：《化学进展》2009年第5期1052-1059,共8页Progress in Chemistry

基　　金：国家自然科学基金项目(No.20675001)资助

摘　　要：电化学DNA生物传感器因快速、灵敏、低耗和易于操作等优点在基因序列测定中受到了广泛的关注,已逐渐成为分子生物学和生物技术研究的重要领域。具有电活性的小分子和纳米材料因它们独特的性质,已被应用于电化学DNA生物传感器中。本文介绍了电化学DNA生物传感器的基本概念和分类,综述了近年来电活性小分子和纳米材料在电化学DNA生物传感器中的应用进展,并对此领域的未来发展做了展望。Owing to the advantages of high sensitivity, rapid response, easy handling and low cost, the electrochemical DNA biosensor has received much attention in the field of genic sequence detection and has gradually become an important field in the study of molecular biology and biological research. Electroactive molecules and nano materials have been applied to the electrochemical DNA biosensors because of their special properties. Here, the principle and classification of the electrochemical DNA biosensors are introduced, and the applications of electroactive molecules and nano materials in electrochemical DNA biosensors in recent years are reviewed. A prospect for the future development in this field is also briefly given.

关 键 词：电化学DNA生物传感器 电活性小分子 纳米材料 

分 类 号：O657.1[理学—分析化学] O629.7[理学—化学]