AECOPD血小板参数变化的临床研究  

Clinical research of the change of platelet parameters of chronic obstructive pulmonary disease with acute exacerbation of changes in platelet parameters

作　　者：常冬梅[1] 

机构地区：[1]临沂市中医医院,山东276002

出　　处：《临床肺科杂志》2009年第6期779-781,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨慢性阻塞性肺病急性加重期(AECOPD)血小板参数的变化及其临床意义。方法对80例AECOPD患者进行血小板计数(PLT)、平均血小板体积(MPV)、血小板压积(PCT)、血小板分布宽度(PDW)的检测,并与稳定期及80例正常对照组进行比较。结果与稳定期及对照组比较,AECOPD患者PLT明显降低(P<0.01),MPV明显升高(P<0.01),血小板压积(PCT)降低(P<0.05),PDW明显增加(P<0.01)。结论血小板参数的检测对慢性阻塞性肺病急性加重期有重要意义,有助于指导临床诊断、治疗及预后评估。Objective To investigate the changes of platelet parameters of chronic obstructive pulmonary disease with acute exac erbation and clinical significance of the changes. Methods The study included 80 patients with chronic obstructive pulmonary disease patients and 80 controls. The measures were platelet count（MLT）, mean platelet volume （MPV）, platelet hematocrit （PCT）, platelet distribution width （PDW） both in the acute exacerbation period and stable period. Results Compared with the control group and with the period of the disease stability, chronic obstructive pulmonary disease patients in the acute period had significantly lower PLT, （P 〈 0. 01 ）, significantly higher MPV （P 〈0. 01 ）. Lower platelet hematocrit （PCT） （P 〈0. 05）, and PDW （P 〈0. 01 ）. Conclusion The platelet parameters for the detection of chronic obstructive pulmonary disease with acute exacerbation are of significance in helping guide clinical diagnosis, treatment and prognosis.

关 键 词：慢性阻塞性肺病 急性发作期 血小板参数 

分 类 号：R563.9[医药卫生—呼吸系统]