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机构地区:[1]东南大学环境工程系,江苏南京210096 [2]东南大学公共卫生学院,江苏南京210009
出 处:《水处理技术》2009年第5期72-74,90,共4页Technology of Water Treatment
基 金:国家高技术研究发展计划(863)项目(2002AA601130)
摘 要:为了评价生物活性炭处理微污染原水的安全性,应用人类乳腺癌(MCF-7)细胞增殖试验和子宫增重试验进行测定。结果表明,水源水及生物活性炭进水提取物能刺激MCF-7细胞增殖,在原水量270mL和810mL时细胞增殖效应达到最大,生物活性炭出水提取物不引起MCF-7细胞增殖;水源水及生物活性炭进水提取物为5、25L·kg-1和25、125L·kg-1剂量组均刺激大鼠子宫生长,与对照组比较有统计学意义。生物活性炭出水提取物对子宫增重无影响,未表现出类雌激素活性作用。In order to evaluate the security of micro-polluted source water by biological activated carbon(BAC) process, MCF-7 cell proliferation assay and uterotropic assay were performed to detect the estrogen-like activity of the component of water. The results showed that the organic extract from source water and water of conventional drinking water processes stimulated the proliferation of MCF-7 cell. The dose inducing the maximum effect in cell proliferation assay was 270mL and 810mL. Organic extract from micro-polluted source water by BAC process did not stimulate the proliferation of MCF-7 cell. In uterotropic assay, doses of 5L·kg^-1, 25 L·kg^-1 and 25 L·kg^-1, 125 L·kg^-1 of organic extract from source water and water of conventional drinking water processes increased the weight of uterus of 21 day female rat significantly. Organic extracted frommicro-pollutedsouree water by BAC process did not exhibit the estrogenic effect.
关 键 词:生物活性炭 微污染原水 细胞增殖试验 子宫增重试验
分 类 号:X522[环境科学与工程—环境工程] TQ424.1[化学工程]
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