我国九省区2006年札如病毒流行状况及基因序列分析  

Analysis of Epidemiologic Feature and Genetic Sequence of Sapovirus in China

作　　者：常昭瑞[1] 靳淼[1] 刘娜[1] 谢华萍[1] 崔淑娴[1] 章青[1] 段招军[1] 

机构地区：[1]中国疾病预防控制中心病毒病预防控制所,北京100052

出　　处：《病毒学报》2009年第2期113-116,共4页Chinese Journal of Virology

基　　金：国家863课题(2002A639470)

摘　　要：为了研究我国札如病毒(Sapovirus,SV)的流行情况及变异特点,收集了2006年2月至2007年1月安徽省、福建省、海南省、河北省、河南省等9个地区5岁以下腹泻患儿的粪便标本共1 110份,应用逆转录-聚合酶链反应(RT-PCR)对札如病毒进行检测,结果表明,札如病毒阳性率为0.9%。对检测到的全部10株札如病毒进一步进行系统进化分析,表明这10株札如病毒属于三个基因型:GI/1、GI/3和GII/3。To investigate epidemiologic feature and genetic variance of Sapovirus among children in China, fecal specimens were collected from children under 5 years old with acute diarrhea from Feb 2006 to Jan 2007 in nine provinces including Anhui, Fujian et ah A total of 1110 fecal samples were detected for Sapovirus by reverse transcriptase-PCR （RT-PCR）. Ten samples （0.9 %） were positive for Sapovirus. The PCR products were then sequenced and analysed by phylogenetic tree. The results indicated that the detected Sapovirus strains were classified into two genogroups and three genotypes, including G I/I,G I/3,G II/3.

关 键 词：札如病毒 杯状病毒 流行病学 基因分型 

分 类 号：R373.2[医药卫生—病原生物学]