神经梅毒9例临床分析  

The Clinical Analysis of the 9 Cases with Neurosyphilis

作　　者：张宇[1] 丁克云[1] 包为政[1] 马朝东[1] 尹雪峰[1] 

机构地区：[1]江苏大学附属人民医院,江苏镇江212003

出　　处：《中国皮肤性病学杂志》2009年第5期300-301,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的分析神经梅毒的临床特征,探讨其诊断及治疗。方法回顾性分析9例神经梅毒患者的临床和实验室资料。结果9例患者中男7例,女2例,7例男性患者有非婚性生活史,2例女性患者其配偶有梅毒。9例患者血清、脑脊液RPR及TPHA均阳性。青霉素是治疗首选。结论神经梅毒根据不同类型有多种发病形式,首诊易误诊及忽视,血清和脑脊液梅毒抗体检查阳性可确诊。青霉素为首选治疗药物。Objective To investigate the clinical manifestations, diagnosis and management of neurosyphilis. Methods The clinical features, neuroimages, laboratory findings and therapy of 9 patients with neurosyphilis were analyzed retrospectively. Restilts Of the 9 cases with neurosyphilis, 7 cases were males, and had a history of frequent sex outside marriage. 2 cases were females, and her spouses were neurosyphilis. All 9 cases of neurosyphilis, rapid plasma reagin circle card test （RPR） and treponema pallidum hemagglutination assay（TPHA） test of both serum and CSF samples were positive, Penicilin was the first choice for effective treatment. Conclusions Patients with neurosyphilis may present diverse clinical symptoms at the beginning of the course, therefore it is misdiagnosed easily at the first visit. It is important to comprehend that positive syphilis antibody test in serum and CSF is specific for the diagnosis. Penicilin is the first choice for effective treatment.

关 键 词：神经梅毒 青霉素 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]