带状疱疹及其后遗神经痛治疗与预防  

An update on the treatment and prevention of herpes zoster and postherpetic neuralgia

作　　者：方丽[1] 吴贤杰[1] 

机构地区：[1]浙江大学医学院附属第二医院皮肤科,杭州310009

出　　处：《国际皮肤性病学杂志》2009年第3期173-175,共3页International Journal of Dermatology and Venereology

基　　金：浙江省医药卫生科技计划项目（2007A090）

摘　　要：带状疱疹及带状疱疹后遗神经痛是皮肤科引起神经性疼痛的常见原因，其治疗和预防是常见临床问题。抗病毒药物能够降低疱疹严重程度、缩短疱疹持续时间，但对带状疱疹后遗神经痛的作用尚不明确。糖皮质激素、三环类抗抑郁药、抗惊厥剂、镇痛药等均能减轻带状疱疹相关疼痛。抗惊厥剂、麻醉性镇痛药、三环类抗抑郁药及局部用利多卡因贴剂和辣椒素软膏均对带状疱疹后遗神经痛有效。接种水痘一带状疱疹疫苗对带状疱疹及带状疱疹后遗神经痛的发病率有重要影响。Herpes zoster and postherpetic neuralgia （PHN） are common causes of neuropathic pain, their treatment and prevention are usually troublesome. Antiviral drugs have been consistently found to effectively reduce the severity and duration of herpes zoster. However, there is no convincing evidence that antiviral agents could reduce the risk of PHN. It is reported that the acute pain of herpes zoster can be relieved by corticosteroids, tricyclic antidepressants, anticonvulsants and analgesics, and PHN can be alleviated by anticonvulsants, narcotic analgesics, tricyclic antidepressants, lidocaine patch 5% and capsaicin ointment. Prophylactic vaccination with herpes zoster vaccine may have a beneficial effect on the incidence of herpes zoster and PHN.

关 键 词：疱疹 带状 神经痛 治疗 

分 类 号：R752.12[医药卫生—皮肤病学与性病学]