撒坝猪ESR和FSH-β基因多态性及其与产仔数的关联分析  

Polymorphisms of ESR and FSH-β Genes and Their Association with Litter Sizes of Saba Pigs

作　　者：鲁绍雄[1] 胡晓湘[2] 连林生[1] 吴常信[3] 严达伟[1] 李宁[2] 任文辉 赵中保 

机构地区：[1]云南农业大学动物科学技术学院,云南昆明650201 [2]中国农业大学农业生物技术国家重点实验室,北京100193 [3]中国农业大学动物科学技术学院,北京100193 [4]云南省楚雄州种猪场,云南楚雄675000

出　　处：《云南农业大学学报（自然科学版）》2009年第3期389-393,424,共6页Journal of Yunnan Agricultural University:Natural Science

基　　金：云南省院省校科技合作项目(00YN01)资助

摘　　要：在对762头撒坝猪的ESR和FSH-β基因多态性进行检测的基础上,系统地分析了两个基因座位的基因型及其合并基因型产仔数的影响。结果表明,撒坝猪ESR基因座位的BB基因型和B等位基因的频率最高,FSH-β基因座位的AA基因型和A等位基因的频率最高。在初产胎次的产仔数上,ESR基因以AA型最多(P<0.05或P<0.01),FSH-β基因则以BB型最多(P<0.05或P<0.01),呈现显著的加性遗传效应(P<0.05);在经产胎次的产仔数上,ESR基因以AB型最高(P<0.05),表现出显著的显性遗传效应(P<0.05或P<0.01),FSH-β基因的3种基因型间则无显著差异(P>0.05)。ESR与FSH-β合并基因型为AABB型的母猪,其初产总仔数及活仔数最多(P<0.05或P<0.01);AAAB型母猪的经产总仔数与活仔数也明显高于其他基因型(P<0.05或P<0.01)。ESR和FSH-β基因确实与猪产仔数存在一定关联,但ESR基因对产仔数的效应与前人关于ESR BB型为猪产仔数增效基因型的结果明显不同。Based on the detection of polymorphisms of estrogen （ESR） and follicle stimulating hor- mone -βsubunit （ FSH -β） genes of 762 Saba pigs, the effects of the two genes on litter sizes were analyzed. The results showed that the frequencies of genotype BB and allele B on ESR gene and genotype AA and allele A on FSH -βgene were the highest in Saba pigs. In the first parity, the total number born （TNB） and the number born alive （NBA） of genotype AA of ESR gene and genotype BB of FSH -β gene were higher than the other two genotypes （ P 〈 0. 05 or P 〈 0. 01 ）, and showed significantly additive effects （P 〈 0.05） . In the later parities, the litter sizes of genotype AB of ESR gene were the highest （P 〈0. 05）, and showed significant dominance effects （P 〈0. 05 or P 〈0. 01 ）, however, it had no significant differences between different genotypes on FSH-β gene （ P 〉 O. 05 ） . The TNB and NBA of the combined genotype ESR AA and FSH -β BB （AABB） were higher than those of other genotypes （P 〈0. 05 or P 〈0. 01 ） in first parity, the TNB and NBA of the combined AAAB were the highest among all genotypes （P 〈 0.05 or P 〈0.01 ）in later parities. The association of ESR and FSH-β gene with litter sizes were confirmed in the present study, however, the effects of ESR gene on the litter size of Saba pigs were obvious different with the previous results.

关 键 词：撒坝猪 ESR基因 FSH-β基因 产仔数 关联分析 

分 类 号：S828.2[农业科学—畜牧学]