催化加氢制备对氨基乙酰苯胺  

Preparation of p-Aminoacetanilide by Catalytic Hydrogenation

作　　者：李玉涵[1] 侯洁[1] 王越[1] 吕连海[1] 

机构地区：[1]大连理工大学精细化工国家重点实验室,大连116012

出　　处：《染料与染色》2009年第2期42-45,共4页Dyestuffs and Coloration

摘　　要：采用高速淬冷法制备了催化剂前体Ni-M-Al合金,经碱活化处理后得到改性骨架镍催化剂。将该催化剂用于对硝基乙酰苯胺(p-NAT)液相加氢制备对氨基乙酰苯胺(p-AAT)的反应。考察了溶剂、原料及催化剂用量、反应温度、系统压力对反应的影响,以及不同反应温度下p-NAT浓度与反应时间的关系曲线,并优化了反应条件。以甲醇为溶剂,在60℃,1.0MPa,m(催化剂)/m(p-NAT)=1/10时,反应24分钟,p-NAT的转化率为100%,p-AAT的选择性达99.5%。p-Nitroacetanilide （p-NAT） was hydrogenated to p-aminoacetanilide （p-AAT） using modified skeletal nickel （S-Ni） as catalyst. The modified S-Ni catalyst was prepared through activation treatment of rapidly quenched Ni-M-Al alloy precursor in NaOH solution. Effects of solvent, amount of catalyst and substrate, reaction temperature and pressure on the reaction, as well as concentration of p- NAT as a function of reaction time under different reaction temperatures, were studied. Under the optimized conditions （60℃, 1.0 MPa, re（cat. ）/m（p-NAT） = 1/10 and methanol as solvent） ,99.5% selectivity of p-AAT with 100% p-NAT conversion was obtained in 24 minutes.

关 键 词：淬冷合金 改性骨架镍催化剂 对硝基乙酰苯胺 对氨基乙酰苯胺 催化加氢 

分 类 号：TQ612[化学工程—精细化工]