“6.25”^(60)Co源辐射事故病人远后效应6年随访观察综合报告  

Six years follow up study of delayed consequences in five patients having survived from Shanghai 60Co radiation accident.

作　　者：章卫平[1] 刘本俶[1] 金璀珍[2] 夏寿萱[2] 张家庆[1] 郭峰[1] 闵锐[3] 蒋本荣 许燕群[1] 李川晟[1] 李津婴[1] 韩丽荣[1] 颜永碧[3] 许国铭[1] 朱德增[1] 沈茜[1] 

机构地区：[1]第二军医大学长海医院 [2]北京放射医学研究所 [3]第二军医大学放射医学研究室 [4]北京北太平路医院

出　　处：《中华放射医学与防护杂志》1998年第1期15-2,共1页Chinese Journal of Radiological Medicine and Protection

摘　　要：通过对１９９０年上海发生的“６．２５”６０Ｃｏ源辐射事故所致的５名骨髓型急性放射病患者系统随访观察，探讨电离辐射引起的远后效应及其性质程度和与剂量的关系等。方法持续６年对患者进行临床表现、造血功能、染色体畸变、免疫功能、神经系统、内分泌功能、生殖功能及眼晶体等检查和ＨＰＲＴ基因突变及某些癌基因检测。结果发现患者在上述诸方面仍存在不同程度辐射损伤，部分损伤程度与受照剂量有关。结论本组患者的研究结果，不仅为患者的医疗保健提供了依据，而且为人的骨髓型急性放射病远后效应研究提供了可靠信息和积累宝贵资料。Objective This article summarizes the six years’ observation and follow up of the five cases of bone marrow form of acute radiation sickness (2 of severe degree and 3 of moderate degree) who survived from Shanghai 60~Co radiation accident in order to inquire into the delayed consequences of radiation,and its relationship to the irradiation dose.Methods Systematic observations of clinical manifestations,hematopoietic function,chromosomal aberrations,immunologic neurological,endocrinological,reproductive functions,eye examination,asssay of HPRT gene mutation and detection of oncogenes were performed in the past six years.Results Varying degrees of radiation lesions in the above aspects were found in these patients.Some of the lesions were related to the irradiation dose.Conclusion These results provide not only scientific basis for patients’ medical treatment and health care,but also reliable information for further study of the delayed consequences of bone marrow form of acute radiation sickness and accumulate a lot of data.

关 键 词：辐射事故 急性放射病 远后效应 随访 钴60 

分 类 号：R818.71[医药卫生—放射医学]