硝普钠复合艾司洛尔控制性降压用于腹主动脉瘤腔内修复术的临床观察  

Effect of combining sodium nitroprusside with esmolol on controlled hypotension in endovascular exclusion of abdominal aortic aneurysm

作　　者：王慧明[1] 于涛[1] 李文锋[1] 

机构地区：[1]成都军区昆明总医院麻醉科,云南昆明650032

出　　处：《华夏医学》2009年第1期7-9,共3页Acta Medicinae Sinica

摘　　要：目的:观察硝普钠复合艾司洛尔控制性降压对腹主动脉瘤腔内修复术患者血流动力学的影响。方法:20例择期腹主动脉瘤腔内修复术患者随机分为两组,组采用单纯硝普钠控制降压;组用硝普钠复合艾司洛尔控制降压。观察降压前、降压后5,10,15min及停药后5,10,15min,患者的SBP、RPP、HR及CVP值,同时记录两组降压开始至降到目标血压时间。结果:组和组从降压开始至目标血压的时间分别为(4.9±1.1)min和(3.7±0.8)min(P<0.05),组患者HR在降压后5,10,15min及停止降压后5min均低于I组(P<0.05)。结论:硝普钠复合艾司洛尔复合使用行控制性降压在腹主动脉瘤腔内修复术中降压平稳,降压中HR无明显增快。Objective ： To investigate the effect of sodium nitroprusside and sodium nitroprusside combined with esmolol in controlled hypotension on endovascular exclusion of abdominal aortic anearysm. Methods ： Twenty patients scheduled for endovascular exclusion of abdominal aortic aneurysm were divided randomly into two groups. Group Ⅰ receiving sodium nitroprusside, group Ⅱ receiving sodium nitroprusside combined with esmolol. The hemodynamics were recorded before controlled hypotension, 5min, 10min, 15min after controlled hypotension and stopping controlled hypotension 5min, 10min, 15min. The time of getting to the target blood pressure were recorded. Results ： The time of getting to the targeted blood pressure was shorter in group Ⅱ [（3.7±0.8）min] than that of group Ⅰ（4.9±1.1） min],P〈0. 05. HR and RPP in group Ⅱ were lower than that of group Ⅰ at 5min,10min and 15min of controlled hypotension. After stop controlled hypotension 5min, HR was lower in group Ⅱ than that of group Ⅰ . Conclusion： Hemodynamics could be maintained stable during controlled hypotension of the patients undergoing endovascular exclusion of abdominal aortic aneurysm.

关 键 词：硝普钠 艾司洛尔 控制性降压 腹主动脉瘤 

分 类 号：R543.16[医药卫生—心血管疾病]