正常视神经MR扩散张量成像扫描参数初步研究  

The preliminary study on scanning parameters of MR diffusion tensor imaging in normal optic nerve

作　　者：宛四海[1] 肖新兰[2] 尹建华[2] 张雪林[3] 

机构地区：[1]解放军171医院放射科,江西九江332000 [2]南昌大学第二附属医院磁共振室,江西南昌330006 [3]南方医科大学附属南方医院影像中心,广东广州510515

出　　处：《医学影像学杂志》2009年第4期391-394,共4页Journal of Medical Imaging

基　　金：九江市科技基金(20070091);江西省卫生厅科技基金(20081063)

摘　　要：目的:探讨视神经MR扩散张量成像最佳的扫描参数,获得最佳的图像质量。方法:采用GESigna Twin1.5T超导磁共振扫描仪,头颅8通道相控阵线圈,单次激发ZOOM自旋回波平面成像序列,选择30例正常成人志愿者,随机分为三组,使用不同的扩散敏感梯度方向数、b值和层厚/层间距,对视神经进行MR扩散张量成像研究。将扩散张量成像原始数据输入个人计算机,应用Volume-one1.72软件进行后处理。结果:扩散敏感梯度方向数为13个方向、b值1000s/mm2、层厚/层间距为3/0mm的扫描参数,可以获得高质量的视神经扩散张量图像,图像清晰,信躁比高,无明显伪影及扭曲、变形。结论:本研究初步建立了视神经最佳的磁共振扩散张量成像扫描参数,获得的图像清晰,能够满足临床研究和应用的需要。Objective：To search for the optimal scanning parameters for MR diffusion tensor imaging in tile study of tile optic nerve. Methods：Images were acquired with a 1.5 T GE Signa Twin MR scanner with 8-clannel head phased array coil using a single-shot zonal oblique muhislice echoplanar imaging （ZOOM-EPI）. 30 cases of healthy volunteers who were divided three groups randomly were studied with using different diffusion-sensitive gradient directions, b value, and slice tificlaless/interval. Primary data of diffusion tensor imaging were processed off-line in file personal computer, with the post-processing software of the Volume-one 1.72.Results：When the parame- ters of MR-DTI sequence were 13 directions of diffnsion-sensitive gradients, 1000 s/mm2 of b value and 3/0 nun of tlfiekness/interval paralleling optic nerve scanning, the high quality DT images of directionally encoded color（DEC） maps and fractional anisotropy （FA） maps were acquired with high MR signal-to-noise ratio（SNR） and minimized partial volume effects and motion artifacts such as distortion or deformation of optic nerve. Conclusion：The optimal parameters of optic nerve for MR diffusion tensor imaging （MR-DTI） scanning are established preliminarily in the study. The DTI maps of optic nerve could satisfy the needs of clinical researching and applications.

关 键 词：扩散张量成像 磁共振成像 扫描参数 视神经 

分 类 号：R445.2[医药卫生—影像医学与核医学] R322.85[医药卫生—诊断学]