丙型肝炎感染途径多中心研究结果的Meta分析  

META ANALYSIS ON MULTICENTRAL RESEARCH RESULT OF TRANSMITTING ROUTE OF HCV INFECTION.

作　　者：张再伟[1,2,3] 雷秉钧[1,2,3] 赵连三 范宗华[1,2,3] 

机构地区：[1]山东济宁医学院附属医院 [2]华西医科大学肝炎研究室 [3]华西医科大学流行病学教研室

出　　处：《现代预防医学》1998年第1期26-28,共3页Modern Preventive Medicine

基　　金：CMB资助

摘　　要：本文采用Ｍｅｔａ分析技术对三所医科大学关于丙型肝炎感染途径的配对病例对照研究结果（共１６０对）进行综合分析，以探索丙型肝炎病毒（ＨＣＶ）感染的可能途径。计算合并ＯＲ值，并作χ２检验。合并结果表明：输血及血制品史、肝炎家族史、注射史、外科手术史与ＨＣＶ感染关系密切（合并ＯＲ值依次为２．４、４．８５、６．７９、１．９６）。而既往肝病史与ＨＣＶ感染无关（Ｐ＞０．２５）。提示：在丙肝的传播中，仍以输血和血制品为主要危险因素，而其它传播途径也不可忽视。 In order to explore the possible transmitting route of HCV infection,use Meta analysis method to combine three medical universitys matched casecontrol study results on the transmitting route of HCV infection.Calculate the combined OR values and take chisquare test.The combined results show:blood transfusion and blood products,family history of hepatitis,history of injection,history of surgical operation are closely related to HCV infection(the combined OR values are 24、485、679、196,respectively).The result shows that the blood transfusion and blood products are the most important transmitting route of HCV infection,and then,other transmitting routes are not ignored.

关 键 词：丙型肝炎病毒 感染途径 META分析 丙型肝炎 

分 类 号：R512.630[医药卫生—内科学]