沙参麦冬汤对运动小鼠免疫功能的影响  

The effect of Radix Ophiopogon soup on the immune function of exercises mice

作　　者：张继红[1] 焦晓明 李儒新[1] 吴红娟[3] 焦丝佳[1] 

机构地区：[1]湘南学院体育系,郴州423000 [2]郴州巿第三人民医院 [3]湖南中医药大学

出　　处：《中国康复医学杂志》2009年第5期442-444,共3页Chinese Journal of Rehabilitation Medicine

基　　金：湖南省教育厅科学研究项目(08C802)

摘　　要：目的:探讨沙参麦冬汤对运动小鼠免疫功能的影响。方法:40只雄性昆明种小鼠,随机分为4组:安静对照组、运动对照组、运动+小剂量沙参麦冬汤组、运动+大剂量沙参麦冬汤组,运动小鼠递增负荷游泳训练40d,游泳时间由40min开始渐增至100min,第40天游泳至力竭,24h后处死取血。测定小鼠免疫器官脏器/体重比值、外周血免疫球蛋白、外周血T细胞亚群。结果:服药组小鼠脾指数、外周血IgG、IgA、CD4+T细胞百分比、CD4+/CD8+比值均显著高于运动对照组(P<0.01或P<0.05);大剂量组小鼠胸腺指数、血清IgM值显著高于运动对照组(P<0.05)。结论:沙参麦冬汤具有提高大强度耐力训练小鼠免疫力的作用。Objective：To study the effect of Radix Ophiopogon soup on the immune function fo exercises mice. Method： Forty male Kunming mice were randomly divided into 4 groups： quiet control group, exercises control group, exercises ＋ Radix Ophiopogon soup of low-dose group, exercises ＋ Radix Ophiopogon soup of high-dose group. The exercises mice swam with progressively increased load for 40d, Twenty-four h after the last exhaustive swimming, the mice were sacrificed. The changes of immune organs/body weight ratio, the peripheral blood immunoglobulin, and peripheral blood T lymphocytes subsets of mice were determined. Result： Spleen index, peripheral blood IgG, IgA, CD4^＋T cells percentage and CD4^＋/CD8^＋ ratio in two drug groups were significantly higher than that in exercises group （P〈0.01 or P〈0.05）; Hymus index, serum IgM of high-dose group were significantly higher than that in exercises group （P〈0.05）. Conclusion： Radix Ophiopogon soup could enhance the immunity of mice with strong endurance training.

关 键 词：沙参麦冬汤 免疫器官 T淋巴细胞亚群 免疫球蛋白 

分 类 号：G804.7[文化科学—运动人体科学]