耐亚胺培南铜绿假单胞菌医院感染现状及耐药性分析  

Nosocomial Infection and Antimicrobial Resistance of Imipenem-resistant Pseudomonas aeruginsoa

作　　者：陈亮[1] 郑颖[2] 马冬媛[1] 辛续丽[1] 韩静[1] 王岩[1] 

机构地区：[1]北京世纪坛医院临检中心,北京100038 [2]襄樊市中心医院核医学科,湖北襄樊441021

出　　处：《中华医院感染学杂志》2009年第9期1131-1132,1168,共3页Chinese Journal of Nosocomiology

摘　　要：目的探讨耐亚胺培南铜绿假单胞菌(IRPA)医院感染的临床现状及耐药性,为临床医师诊断与治疗提供科学依据。方法调查IRPA医院感染患者的临床资料;将住院患者感染性标本中分离出的铜绿假单胞菌(PAE),采用KB法进行体外耐药监测,并统计耐药率。结果2年来医院感染性标本中共检出336株IRPA,占PAE总数的38.7%,IRPA对常用抗菌药物耐药率明显高于非亚胺培南耐药株。结论建议重视对IRPA的监测与控制,尤其要关注泛耐药菌株的产生与流行。OBJECTIVE To investigate nosocomial infection status and antibiotic resistance of imipenem-resistant Pseudomonas aeruginosa （IRPA） to provide scientific evidence for clinical diagnosis and treatment. METHODS The clinical data of the patients infected with IRPA were investigated. P. aeruginosa （PAE） was isolated from inpatients/ specimen and antibiotic susceptibility test in vitro was performed by K-B methods. RESULTS During two years, 336 strains of IRPA were identified, accounting for 38. 7%. The resistance rates to the common antibiotics in IRPA were significantly higher than that in non-IRPA strains. CONCLUSIONS It suggests that we think highly of monitoring and controlling of IRPA and pay close attention to the occurrence and prevalence of pan- drug resistant strains especially.

关 键 词：医院感染 铜绿假单胞菌 亚胺培南 抗药性 

分 类 号：R978.1[医药卫生—药品]