常见革兰阴性杆菌的耐药性分析  

Antibiotics Resistance Analysis of Gram-negative Bacilli

作　　者：张妍蓓[1] 何凤莲[1] 方明[1] 华天风[1] 胡碧丹[1] 徐元宏[1] 刘荣玉[1] 

机构地区：[1]安徽医科大学第一附属医院老年呼吸内科,安徽合肥230022

出　　处：《中华医院感染学杂志》2009年第9期1143-1145,共3页Chinese Journal of Nosocomiology

基　　金：安徽省高校省级自然科学基金(KJ2008A157)

摘　　要：目的了解临床分离的常见革兰阴性杆菌的分布及耐药情况,为临床合理用药提供依据。方法对2006年1-12月临床送检各类标本中培养分离的697株常见革兰阴性杆菌,采用WalkAway-40全自动细菌鉴定及药敏测试仪以及NC31鉴定板进行分析。结果最常见的革兰阴性菌株为铜绿假单胞菌、大肠埃希菌、肺炎克雷伯菌、阴沟肠杆菌、鲍氏/溶血不动杆菌与嗜麦芽寡养单胞菌,其检出率分别为24.25%、23.67%、21.67%、11.33%、10.90%与8.18%,从总的耐药情况显示,革兰阴性杆菌(除嗜麦芽寡养单胞菌外)对亚胺培南耐药率最低。结论医院革兰阴性杆菌耐药严重,临床要定期进行细菌耐药监测,合理使用抗菌药物。OBJECTIVE To investigate the resistance and distribution of the Gram-negative bacilli and conduct clinical medication. METHODS A total of 697 strains of Gram-negative bacilli isolated from the all sorts of samples from Jan 2006 to Dec 2006 were analyzed by WalkAway-40 system with NC31 system. RESULTS The dominant strains were Pseudornonas aeruginosa , Escherichia coli , Klebsiella pneurnoniae , Enterobacter cloacae, Acineto- bacter baumannii and Stenotrophornonas maltophili. The resistance rate of the main Gram-negative bacilli against imipenem was the lowest. CONCLUSIONS Most of Gram-negative bacilli in nosocomial infection are highly resistant to drugs. It is very important to use antibiotics reasonably against nosoeomial infection.

关 键 词：革兰阴性杆菌 抗菌药物 耐药率 

分 类 号：R378[医药卫生—病原生物学]