尿视黄醇结合蛋白的检测及临床应用  

Detection and clinical application of urinary retinol-binding protein

作　　者：唐璋琳[1] 陈挺尧[1] 刘美绸[1] 

机构地区：[1]福建三明市第二医院,366000

出　　处：《陕西医学检验》1998年第1期52-53,共2页Shaanxi Journal of Medical Laboratory Sciences

摘　　要：对105例病人进行酶免法测定尿视黄醇结合蛋白（RBP），糖尿病组25例尿RBP排泄增高，阳性率为43％，其中11例伴尿Alb同时增高占19％，另14例尿Alb正常，RBP排泄阳性率为29％；高血压病组7例，RBP与Alb同时增高，阳性率21％；肾小球肾炎组3例RBP与Alb同时增高，阳性率21％；糖尿病与高血压及肾小球肾炎对比有显著差别（P＜0．05），表明尿RBP测定是肾小管损害的一项敏感指标。　105 patients were detected Urinary Retinol-Binding protein (RBP) by Enzyme Immunoassay (EIA). In diabetic group, 25 cases Excretion of RBP in the urine was increased,positive rate was 43%. 11 albumin(Alb) al-so increased. Positive rate of excretion of RBP was 29 % ;in hypertension group, 7 cases RBP and Alb increased atthe same time,Positive rate was 21 % ; Glomerulone nephritis group,3 cases RBP and Alb increased,positive rate21 %. There was obvious difference in diabetic,hypotension glomerulone nephritis (P<0. 05). RBP in the urine isa sensitive index of renal tubules injured.

关 键 词：视黄醇结合蛋白 酶免测定法 肾小管损害 RBP 

分 类 号：R446.12[医药卫生—诊断学]