Synthesis of di-and tetrasaccharide containing 6-deoxytalose from the O-antigenic polysaccharide of B. pseudomallei strain 304b  

作　　者：Shi Qiang Yan Xue Min Wu Xiao Mei Liang Jian Jun Zhang Dao Quan Wang 

机构地区：[1]Key Lab of Pesticide Chemistry and Application Technology, Department of Applied Chemistry, China Agricultural University, Beijing 100193, China

出　　处：《Chinese Chemical Letters》2009年第5期582-585,共4页中国化学快报（英文版）

基　　金：supported by the Doctoral Program Foundation of Institutions of Higher Education of China(No:20070019072).

摘　　要：Synthesis of the disaccharide [3-D-Glup-（1→3）-6-deoxy-α-L-Talp Ⅱ, and its dimer Ⅲ from the O-antigenic polysaccharide of Burkholderia pseudomallei strain 304b, were achieved through assembly of suitably synthesized building blocks, 4-methox- ylphenyl 6-deoxy-2,4-di-O-benzoyl-α-L-talopyranoside （7）, 3-O-allyl-2,4,6-tri-O-benzoyl-α,β-D-glucopyranosyl trichloroacetimi- date （8） and 2,3,4,6-tetra-O-benzoyl-α,β-D-glucopyranosyl trichloroacetimidate （11）. The total yield of Ⅲ from 4-methoxylphenyl 2.3-O-isopropvlidene-α-L-rhamnoovranoside （1） was 18%.Synthesis of the disaccharide [3-D-Glup-（1→3）-6-deoxy-α-L-Talp Ⅱ, and its dimer Ⅲ from the O-antigenic polysaccharide of Burkholderia pseudomallei strain 304b, were achieved through assembly of suitably synthesized building blocks, 4-methox- ylphenyl 6-deoxy-2,4-di-O-benzoyl-α-L-talopyranoside （7）, 3-O-allyl-2,4,6-tri-O-benzoyl-α,β-D-glucopyranosyl trichloroacetimi- date （8） and 2,3,4,6-tetra-O-benzoyl-α,β-D-glucopyranosyl trichloroacetimidate （11）. The total yield of Ⅲ from 4-methoxylphenyl 2.3-O-isopropvlidene-α-L-rhamnoovranoside （1） was 18%.

关 键 词：OLIGOSACCHARIDE GLUCOSE RHAMNOSE 6-Deoxytalose 

分 类 号：TQ336.41[化学工程—橡胶工业] Q939.124[生物学—微生物学]