坦索罗辛治疗输尿管下段结石的临床疗效观察  

Clinical Efficacy of Tamsulosin in the Treatment of Patients with Lower Ureteral Stones

作　　者：李新 

机构地区：[1]湖南省岳阳市二人民医院泌尿外科,湖南岳阳414000

出　　处：《医学临床研究》2009年第4期661-662,共2页Journal of Clinical Research

摘　　要：【目的】探讨坦索罗辛治疗输尿管下段结石的临床疗效。【方法】对门诊180例输尿管下段结石患者进行分组治疗，1组为对照组86例，U组为治疗组94例。两组均每日饮水2000ml以上，服用左氧氟沙星0．2，2次1日，治疗组加用盐酸坦索罗辛0．2，2次／日，疗程4周。【结果】治疗组结石排出率为72．3％（68/94），对照组结石排出率为31．3％（27／86）；两组比较排石率有统计学差异（P〈0．05）。平均排石时间治疗组为（6±2）d，对照组为（15±3）d，2纽比较有统计学差异（P〈0．05）。【结论】坦索罗辛治疗输尿管下段结石安全、有效，能明显提高排石率。[Objective]To explore the efficacy of tamsulosin in the treatment of patients with lower ureteral stones. [Methods] A total of 180 patients with lower ureteral stones were randomly divided into two groups. Group I （n=86） served as control and group Ⅱ （n=94） received tamsulosin （0.4mg, once daily）. All pa tients were observed for 4 weeks. [Results]The successful stone expulsion rate in group I and group [1 was 72.3%（68/94）and 31.3%（27/86）, respectively. The mean expulsion time of group I and group Ⅱ were （15±3） days and （6±2） days, respectively. There were statistically significant differeuce between two groups （P〈0.05）. [Conclusion]Tamsulosin is safe and effective for lower ureteral stones. It can significantly improve the stone expulsion rate.

关 键 词：输尿管结石/药物疗法 肾上腺素能α拮抗剂/治疗应用 

分 类 号：R693.4[医药卫生—泌尿科学]