光声结构与功能成像技术研究进展  

Progress on Photoacoustic Structural and Functional Imaging

作　　者：袁毅[1] 向良忠[1] 

机构地区：[1]华南师范大学激光生命科学研究所暨激光生命科学教育部重点实验室

出　　处：《激光生物学报》2009年第2期281-284,F0003,共5页Acta Laser Biology Sinica

基　　金：国家自然科学基金项目(30627003,30870676);广东省自然科学基金项目(7117865)

摘　　要：光声成像技术利用短脉冲激光激发产生光声信号，可重建出组织的光吸收分布图像，它结合了纯光学成像的高对比度和纯声学成像的高分辨率特性。光声成像技术不仅能够有效的刻画生物组织结构，还能够精确实现无损功能成像，为研究生物组织的形态结构，生理、病理特征，代谢功能等提供了全瓶手段。本文简要分析了光声信号产生的机理，总结报道了目前实验室几套典型的成像系统及其最新应用进展，指出光声成像作为一种新型的生物医学成像方法，可望引发生物医学影像领域的一次革新。Photoacoustic imaging technology utilized that the short pulse laser excited photoacoustic signal, and the distribution image of optical absorption of tissue was reconstructed. It takes advantage of high optical contrast and high acoustical resolution. Photoacoustic imaging technology can visualize the structures of biology tissue, and accurately realize noninvasive function imaging, it provides a new method for studying morphology, physiological and pathological features and metabolic function of biology tissue. In this paper, the principle of photoacoustic signal generation was analyzed; some typical imaging systems and progress of the newest application were reported. Photoacoustic imaging as a new biomedical imaging method could potentially initiate an innovation in the biomedical imaging field.

关 键 词：生物医学成像 光声成像 结构与功能成像 成像系统 

分 类 号：R318.51[医药卫生—生物医学工程]