几种β-二酮类化合物的氧化偶联反应  

Coupling Reaction of β-Dicarbonyl Compounds

作　　者：张书文[1] 张志平[1] 郝鹏鹏[1] 路红凯[1] 

机构地区：[1]河北大学化学与环境科学学院,河北保定071002

出　　处：《河北大学学报（自然科学版）》2009年第2期160-163,共4页Journal of Hebei University(Natural Science Edition)

基　　金：国家自然科学基金资助项目(20574016)

摘　　要：首先将乙酰丙酮、苯甲酰丙酮、二苯甲酰甲烷等β-二酮类化合物转变成相应的碳负离子,再用四氢呋喃作溶剂,以Br2为氧化剂,进行活性亚甲基的偶联反应,从而合成了3种相应的四羰基化合物,产率依次为91.2%,62.1%和42.6%.对影响反应的相关因素进行了讨论,并确定了最佳反应条件.β-dicarbonyl compounds such as acetylaeetone, benzoylacetone, dibenzoylmethane etc were transformed into corresponding sodium salts firstly, then tetracarhonyl compounds were prepared by the oxidative coupling reaction of active methylene, using the THF as solvent and Br2 as oxidant. The yields were 91.2%, 62.1% and 42.6%, respectively. The factors which influence the reaction were discussed and the optimal conditions were acquired.

关 键 词：Β-二酮 偶联反应 四羰基化合物 

分 类 号：O621.3[理学—有机化学]