3．0TMRI对早期子宫内膜癌的诊断及分期价值  

Clinical value of 3. 0 T MRI diagnosis and staging in early endometrial carcinoma

作　　者：袁晓春[1] 张贵祥[1] 何之彦[1] 胡运胜[1] 沈晨[1] 

机构地区：[1]上海交通大学附属第一人民医院放射科,200080

出　　处：《中华放射学杂志》2009年第5期509-513,共5页Chinese Journal of Radiology

摘　　要：目的探讨3．0TMR T2WI及容积加速肝脏采集扫描（LAVA）技术对早期子宫内膜癌的诊断价值。方法回顾性分析经手术病理证实的27例子宫内膜癌患者资料。MR检查包括横断面T1WI、矢状面脂肪抑制T2WI；横断面或矢状面LAVA动态增强扫描（包括动脉早期、晚期、实质期和延迟期）。记录肿瘤的部位、信号，对子宫肌层浸润深度进行术前分期并与手术病理结果对照，评价T2WI和LAVA序列对子宫内膜癌诊断的敏感度、特异度、准确度，并采用配对卡方检验Fisher’s确切概率法比较2种序列对深肌层浸润的准确性。结果经手术病理证实的27例子宫内膜癌，按国际妇产科联盟标准分为：Ⅰ期22例，Ⅱ期5例。T2WI判断肿瘤深肌层浸润的敏感度、特异度、阳性预测值、阴性预测值分别为70．0％（7／10）、94．1％（16／17）、87．5％（7／8）和84．2％（16／19），准确度为85．2％（23／27）；LAVA判断肿瘤深肌层浸润的敏感度、特异度、阳性预测值、阴性预测值分别为80．0％（8／10）、94．1％（16／17）、88．9％（8／9）和88．9％（16／18），准确度为88．9％（24／27）。2种序列对深肌层浸润的准确度差异无统计学意义（P=1．00）。结论3．0TMR T2WI对早期子宫内膜癌的诊断具有重要作用，LAVA动态增强扫描对早期子宫内膜癌肌层浸润术前诊断及分期有指导价值。Objective To evaluate T2WI sequence and liver acquisition with volume acceleration （LAVA） technique in the diagnosis of early endometrial carcinoma on 3.0 T MR scanner. Methods Twenty-seven patients with endometrial carcinoma confirmed by pathology were retrospectively analyzed. MRI sequences included axial T1WI and sagittal T2WI with fat saturation, axial and sagittal LAVA scanning including four phases： early arterial phase, late arteral phase, parenchymal phase and delayed phase. The tumor location, signal features, and myometrial infiltration by tumor were recorded and preoperative staging was compared with pathologic results. The sensitivity, specificity, accuracy of T2WI and LAVA in diagnosing endometrial carcinoma was assessed. The accuracy of the evaluation of the deep myometrium infiltration was compared between the two sequences using Fisher＇s exact test. Results According to Federation International of Gynecologic and Obstetrigue （FIGO） standard, 27 patients with endometrial carcinoma were classified as： stage Ⅰ in 22 cases, stage Ⅱ in 5 cases. The sensitivity, specificity, positive and negative predictive values in assessing deep myometrium infiltration were 70. 0% （7/10）, 94. 1% （16/17）, 87.5% （7/8）, 84.2% （16/19） respectively for T2WI sequence. Its accuracy in assessing myometrium invasion was 85.2% （23/27）. The sensitivity, specificity, positive and negative predictive values were 80. 0% （ 8/10 ）, 94. 1% （ 16/17 ）, 88. 9% （ 8/9 ）, 88.9% （ 16/18 ） respectively for LAVA sequence, and the accuracy was 88.9% （24/27）. There was no statistical difference of accuracy between two techniques（P = 1.00）. Conclusion 3.0 T MR T2WI sequence has important role in diagnosing early endometrial carcinoma, and LAVA technique is highly valued in preoperative diagnosis and staging in early endometrial carcinoma for myometrium infiltration.

关 键 词：子宫内膜肿瘤 肿瘤分期 磁共振成像 

分 类 号：R686[医药卫生—骨科学]