PPF/(CaSO_4/β-TCP)复合生物材料的制备与表征  

Preparation and characterization of poly(propylene fumarate)/(calcium sulfate/β-tricalcium phosphate) biocomposites

作　　者：邸利芝[1] 刘斌[1] 罗跃娥[1] 赵红[1] 蔡仲雨[2] 

机构地区：[1]天津医学高等专科学校,天津300222 [2]天津大学材料科学与工程学院,天津300072

出　　处：《天津师范大学学报（自然科学版）》2009年第2期50-53,共4页Journal of Tianjin Normal University：Natural Science Edition

基　　金：天津市教委科研计划项目(20071212);天津市科委基础研究重点项目(043803511)

摘　　要：制备了聚富马酸丙二醇酯／（硫酸钙／β磷酸三钙）（PPF／（CaSO4／β-TCP））复合生物材料，研究了PPF的分子量、N-乙烯基吡咯烷酮（NVP）与PPF的质量比、过氧化苯甲酰（BP）与PPF的质量比、CaSO4／β-TCP小球与PPF的质量比对最高交联温度、凝胶时间、复合材料抗压强度和模量的影响。结果表明：所有配方的最高交联温度为38-43℃；凝胶速度随着PPF分子量的增大或BP与PPF质量比的升高而加快，所有配方的凝胶时间为2～12min；复合材料的抗压强度为12～62MPa，抗压模量为160～1149MPa。扫描电镜（SEM）分析表明，CaSO4／β-TCP小球比较均匀地分散在PPF／NVP基体中。A kind of poly （ propylene fumarate） / （ calcium sulfate/β- tricalcium phosphate） （ PPF/（ CaSO4/β-TCP）） biocomposite is prepared. The effects of varying PPF molecular weight, N-vinyl. pyrrolidinone （NVP） to PPF ratio, benzoyl peroxide （BP） to PPF ratio and spherical CaSO4/β-TCP granules to PPF ratio on the maximum cross-linking temperature, gel point and the composite compressive strength and modulus are examined. The results show that the maximum cross-linking temperature ranges from 38 to 43℃ for all formulations. An increase in PPF molecular weight as well as BP to PPF ratio leads to gel more rapidly. The gel point of PPF/（CaSO4/β-TCP） composites varis from 2 to 12 rain. For all formulations, the compressive strength values are between 12 and 62 MPa, and the compressive modulus values are between 160 and 1 149 MPa. The results of SEM show that CaSO4/β-TCP granules uniformly disperse in PPF/NVP matrix.

关 键 词：聚富马酸丙二醇酯 硫酸钙/β磷酸三钙 制备 表征 

分 类 号：O641[理学—物理化学]