未肝素化冠状动脉造影600例安全性临床分析  

Evaluating the clinically safety of non-heparin coronary angiography based on 600 patiens

作　　者：傅宴[1] 张元春[1] 尹庆[1] 吴家宽[1] 戴磊[1] 

机构地区：[1]中山大学附属东华医院心内科,广东东莞523110

出　　处：《临床和实验医学杂志》2009年第5期46-47,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的评价未肝素化冠状动脉造影术的可行性及安全性。方法总结分析600例经股动脉行未肝素化冠状动脉造影术的患者的临床资料,记录手术时间、手术成功率及术中并发症。结果98.5%的病例行选择性冠状动脉造影成功,手术时间(从穿刺动脉到造影结束)8 m in至1 h,平均(17.9±6.3)m in。冠心病阳性率为38.8%,多支血管病变占20.3%。心室纤颤发生率0.5%,造影剂过敏发生率0.17%,造影导管内血栓形成0.83%;鞘管内血栓形成0.5%;皮下血肿,动静脉瘘,腹膜后血肿,脑卒中,急性心肌梗死及死亡等其他严重并发症发生率为0%。结论未肝素化冠状动脉造影术安全可靠,并发症少,可以在经验丰富的临床介入医生中使用,但不宜盲目推广。Objective To evaluate the clinically feasibility and safety of non - heparin coronary angiography. Methods The clinical, data of 600 patients who received non - heparin coronary angiography via the femoral artery were collected, the operation time, success ratio and complication ratio were analyzed. Results The success rate of selective non - heparin coronary angiography was 98.5%. The operation time ranged from 8 minutes to 1 hour （ mean 17.9± 6.3 minutes）. The positive rate of coronary artery disease was 38.8%, and multivessel disease was 20.3% among the total. The incidence rate of ventricular fibrillation was 0.5%, constrast medium hypersensitiveness was 0.17%, thrombogenesis in angiography catheter was 0.83% and thrombogenesis in introducer sheath was 0：5%. While the rate of serious complications such as ecchymoma, arterio - venous fistula, retroperitoneal hematoma, stroke, acute myocardial infarction or death was 0%. Conclusion The nan - heparin coronary angiography is safe and reliable with low complication. It can be generalized among experienced intervention doctors but not blindly.

关 键 词：冠状动脉造影 未肝素化 并发症 

分 类 号：R816.2[医药卫生—放射医学]