无机陶瓷膜分离地龙匀浆液中药效物质的操作条件优化研究  

Study on optimization of operation parameters of microfiltration separation of effective matters in earthworm homogenate using inorganic ceramic membrane

作　　者：戴启刚[1] 金伟成[1] 江沛[1] 詹秀琴[1] 

机构地区：[1]南京中医药大学基础医学院,江苏南京210046

出　　处：《中成药》2009年第5期704-707,共4页Chinese Traditional Patent Medicine

基　　金：江苏省中医药局科学技术研究专项基金(012222005117);江苏省天然药物与创制实验室基金资助(KF2005002)

摘　　要：目的:摸索无机陶瓷膜分离地龙匀浆液中药效物质的最佳操作条件。方法:以膜通量为指标,筛选合适的膜材质,优化压力、温度、浓度等操作条件。结果:显示膜通量随过滤压差、温度增加而呈现上升趋势,随浓度的上升而下降。结论:通过比较膜通量的大小和膜通量的衰减速度,分级分离时一级膜管选择0.2μm Al2O3、二级膜管选择50 nm ZrO2,最佳操作条件:0.15 mPa、50℃、33.3%的料液浓度。AIM ： To aim to seek the best operation conditions of the inorganic ceramic membrane in the separation of effective matters from the homogenate of earthworm. METHODS： The homogenate flux was adopted as index, to select the membrane material, filter pressure,homogenate temperature and concentration. RESULTS ： The experiment showed that the filter flux had a significant positive correlation with pressure difference and liquid temperature, and negative correlation with liquid concentration. CONCLUSION： In the separation of earthworm homogenate, 0.2μm Al2O3 and 50 nm ZrO2 film pipe were respectively selected as primary and secondary separating unit on the condition of 0. 15 mPa pressure, 50 ℃ and 33. % （w/w） homogenate concentration.

关 键 词：地龙匀浆液 无机陶瓷膜 膜分离 

分 类 号：R944[医药卫生—药剂学]