银屑病断肢(指)再植的血管病理观察及临床疗效  

Pathological Observation of Arteries and Clinical Outcomes in Psoriasis Patients with Limb (Finger) Replantation

作　　者：栾夏刚[1] 蔡林[1] 陶圣祥[1] 胡昊[1] 王冶[1] 

机构地区：[1]武汉大学中南医院骨科,湖北武汉430071

出　　处：《武汉大学学报（医学版）》2009年第3期390-392,F0003,共4页Medical Journal of Wuhan University

摘　　要：目的:观察银屑病患者中小动脉的病理变化;评估银屑病患者断肢(指)再植的临床效果。方法:取中小动脉切片行HE染色并观察,采用内、外固定固定肢体离断部分,通过增加吻合静脉数使得吻合静动脉数比例大于传统比例2∶1,并且调整抗银屑病治疗方案。结果:银屑病中小血管中膜增厚,纤维化明显;7例银屑病患者断肢(指)全部成活,其中1例患者术后3 d出现血管危象,给予扩管、抗凝、改善微循环治疗后缓解。结论:通过增加吻合静脉血管数量,增加静脉回流,并调整抗银屑病治疗方案使得银屑病患者断肢(指)获得良好的效果。To observe the pathological changes in small- and medium-sized arteries of psoriasis patients, and to evaluate the clinical effect of limb or finger replantation in psoriasis patients. Methods： Small- and medium sized artery sections were observed with HE staining, the amputated limbs were replanted with internal and external fixations, and more veins were anastomosed to increase the vein/artery rate to more than 2 ： 1, the conventional rate, and adjusted psoriasis treatment at the same time. Results. In psoriasis patients, medium membrane was thickened and fibrosis was shown in small and medium-sized blood vessels. All the replanted limbs or fingers survived, and only one case occurred postoperative vessel thrombosis and treated by changing dressing and neurocutaneous island flap transplantation. Conclusion.. It can get an ideal clinical outcomes of replantation in psoriasis patients by anastomosing more veins to improve venous return and adjusting the treatment of psoriasis at the same time.

关 键 词：银屑病 血管 断肢再植 断指再植 

分 类 号：R65[医药卫生—外科学]