毛细管气相色谱法测定珍珠明目滴眼液中冰片的含量  

Determination of borneol in eye drops by gas chromatography

作　　者：蔡冰[1] 

机构地区：[1]广东药学院,广东广州510006

出　　处：《安徽医药》2009年第5期502-503,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的用毛细管气相色谱法对珍珠明目滴眼液中冰片的含量进行测定。方法采用OV-17毛细管色谱柱（30m×0．32mm×0．25μm）；程序升温，起始温度为90％；进样口温度220℃；FID检测器，检测器温度为220℃。结果用气相色谱法测定该滴眼液其冰片在0．0549—0．2743g·L^-1范围内呈良好的线性关系，线性方程为Y=2．0142X-0．0168，r=0．9999。平均回收率为：98．3％（n=5），RSD=1．9％（n=5）。结论本方法简便、准确。可为同类药品中冰片的含量测定提供实验依据。Aim To establish a gas chromatography（GC） method for the determination of borneol in eye drops. Method A ov-17 column （30 m × 0. 32 mm × 0.25 μm）was used. Column temperature was raised by programming, with original temperature at 90℃ and injector temperature at 220℃. FID temperature is 220℃. Results The linear range of borneol was 0. 0549 - 0. 2743 g ·L^- 1. The average recovery was 98.3 % （ n = 5 ）, and RSD was 1.9% （ n = 5 ）. Conclusion The method is simple and accurate.

关 键 词：滴眼液 冰片 毛细管气相色谱法 

分 类 号：R286[医药卫生—中药学]