附子理中汤治疗恶性肿瘤化疗消化道反应的临床观察  

Clinical observation on efficacy of fuzilizhongtang used for treating gastrointestinal reaction due to chemotherapy for malignant tumor

作　　者：刘秋琳[1] 马秋霞[1] 

机构地区：[1]山东省日照市人民医院,276826

出　　处：《中国临床实用医学》2009年第3期42-44,共3页China Clinical Practical Medicine

摘　　要：目的观察附子理中汤治疗化疗消化道反应的临床疗效。方法对160例接受化疗的肿瘤患者进行临床研究。将160例患者随机分为观察组和对照组各80例，两组选用相同的化疗方案，化疗前均用盐酸格拉司琼静脉点滴止吐，化疗期间观察组每日服用附子理中汤，对照组每日以甲氧氯普胺10mg、苯海拉明20mg肌内注射。结果观察组恶心呕吐、食欲下降、进食差、腹胀、便秘症状发生率低，明显优于对照组，经统计学分析，P〈0．05差异有统计学意义。结论附子理中汤能显著减轻化疗消化道反应，值得临床推广应用。Objective To observe the clinical effect of fuzilizhongtang in Treating gastrointestinal reaction due to chemotherapy for malignant tumor. Methods 160 post-chemotherapy tumor patients treated with the same chemotherapy were randomly divided into two equal groups. The control and the fuzilizhongtang group received the same chemotherapeutic treatments with intravenous Granisetron Hydrochloride before the chemotherapy for preventing vomiting. During the chemotherapy period, the control group were intramuscularly injected with 10 mg metoclopramide and 20 mg Diphenhydramine while the fuzilizhongtang group were given fuzilizhongtang per day orally. Results The incidence of nausea and vomiting, loss of appetite, abdominal distention, constipa- tion was significantly lower in fuzilizhongtang group than in control group（ P 〈 0. 05 or P 〈 0.01 ）. Conclusion Fuzilizhongtang can significantly alleviate the gastrointestinal reaction due to chemotherapy for malignant tumor, deserve the clinical expansion.

关 键 词：附子理中汤 肿瘤 化疗 消化道反应 

分 类 号：R259[医药卫生—中西医结合]