玉嘧磺隆新合成方法研究  

New Synthetic Method of Rimsulfuron

作　　者：童军[1] 郑占英[1] 严东文[1] 王素华[1] 李正名[1] 

机构地区：[1]南开大学农药国家工程研究中心(天津),300071

出　　处：《化工中间体》2009年第5期29-31,共3页

摘　　要：玉嘧磺隆是杜邦公司研发成功的磺酰脲类除草剂。以3-乙基磺酸-2-吡啶磺酰胺为原料,在二氯亚砜的作用下生成亚硫酰吡啶磺酰胺,然后再和三光气反应得到磺酰胺异氰酸酯,不需要提纯直接和2-胺基-4,6-二甲氧基嘧啶加成即得到玉嘧磺隆。此方法提高原子经济性。提供了一条新的合成玉嘧磺隆的方法。Rimsulfuron DuPont company in is a sulfonylurea herbicides that was successfully developed by mid-80. 3-ethylsulfonyl-2-pyridinesulfonamide reacted with dichloro sulfoxide, a N-Sulfinylsulfonamide pyridine was corresponding isocyanate. It was then further obtained, which was reacted with Triphosgene to the reacted 2-amino-4,6-dimethoxypyrimidine without purification to obtain Rimsulfuron. This method provides a new approach to synthesize the target compound.

关 键 词：玉嘧磺胺 玉嘧磺隆 

分 类 号：TQ457.23[化学工程—农药化工]