432例HPV检测结果和宫颈病变的关系分析  

The relationship between the examination results of 432 cases of HPV and the lesion precancerous

作　　者：刘筑玉[1] 李建梅[1] 范燕红[1] 姜亚杰[1] 

机构地区：[1]深圳市宝安区妇幼保健院,518133

出　　处：《中国妇幼保健》2009年第14期1919-1920,共2页Maternal and Child Health Care of China

摘　　要：目的:探讨HC2-HPV-DNA在宫颈癌及癌前病变诊断中的预测价值。方法:应用杂交捕获法HC2-HPV-DNA对432例患者作13种高危型HPV检测,并通过阴道镜对可疑病灶多点活检。结果:432例患者中HC2-HPV-DNA阳性者223例(51.6%),阴性者209例(48.3%);病理活检慢性炎症81例,宫颈癌及癌前病变162例;HPV阳性患者的宫颈癌及癌前病变为52%。结论:利用HC2-HPV-DNA检测13种高危型HPV,有针对性地进行活组织病理检查,有效地指导临床,是诊断宫颈癌及癌前病变的重要手段。Objective： To study the estimation of HC2 - HPV - DNA in the cancer of the cervix and the lesion precancerous. Methods： Hybrid capture HC2- HPV- DNA was used to determine the 13 high- risk of human papillomavirus （HPV） in 432 women. The multiple punch biopsy was examined by colposcope in the doubtful cervical tissues. Results ： The positive of HC2 - HPV - DNA was 51.6% （223/432）, the negative of HC2 - HPV - DNA was 48. 4% （209/432） ; the chronic inflammation were 18.8% （81/ 432） , the cancer of the cervix and the lesion precancerous were 37. 5% （162/432） ; the cancer of the cervix and the lesion precancerous was 39. 0% in the positive of HPV. Conclusion： Hybrid capture HC2 -HPV -DNA can detect the 13 high -risk HPV. It＇s a important method to diagnose the cervix and the lesion precancerous with the pathology biopsy.

关 键 词：HC2一HPV—DNA 宫颈癌 宫颈癌前病变 

分 类 号：R711.74[医药卫生—妇产科学]