Screening and Efficacy Observation of Traditional Chinese Medicine Against Chicken Pathogenic Escherichia coli  

抗鸡致病性大肠杆菌中药的筛选及其疗效观察(英文)

作　　者：庞向红[1,2] 褚秀玲[3] 苏建青[3] 梁淑珍[2] 李全福[2] 胡满[1] 

机构地区：[1]河北农业大学动物科技学院,河北保定071001 [2]河北北方学院动物科技学院,河北张家口075131 [3]聊城大学农学院,山东聊城252059

出　　处：《Agricultural Science & Technology》2009年第1期140-144,共5页农业科学与技术（英文版）

基　　金：Supported by Fund of Education Department in Hebei Province(2007408)~~

摘　　要：[ Objective] The aim of this study was to lay a foundation for obtaining effective traditional Chinese medicine preparations controlling chicken colibacillosis. [ Method] With the western medicine Lomeflbxacin Hydrochloride and Sodium Chloride Injection as the control, drug sensitivity tests of 15 single traditional Chinese herbs and seven self-made Chinese herbal compounds were conducted. Subsequently, the single traditional Chinese herbs presenting good in vitro antibacterial effects against Escherichia coli and all the seven compounds were given to the chicks artificially infected with E. coil to observe their efficacies. [ Result] The results of drug sensitivity tests showed that all the 15 traditional Chinese herbs had certain antibacterial effect against E. coli, among which aloe, pomegranate rind and radix sanguisorbae were the best. Compound 1, 2 and 5 had good antibacterial effects in vitro. By in vivo test, traditional Chinese medicines showed superior efficacies on infected chicks than western medicine, and compound 1 and 2 performed well. [ConclusiOn] Traditional Chinese medicine preparations are good at controlling Chicken colibacillosis, but their bacteriostasis mechanism in vivo was different with that in vitro.1材料与方法1．1材料1．1．1供试动物。1日龄雏鸡，常规雏鸡饲料隔离平面笼养至7日龄（鸡苗和饲料皆购自河北北方学院实验牧场）。

关 键 词：Traditional Chinese medicine preparation Drug sensitivity test Chicken colibacillosis In vivo test 

分 类 号：S858.31[农业科学—临床兽医学]